Evidence for the convergence of β-adrenergic and muscarinic signalling systems at a post-receptor site

The β-adrenergic agonist isoproterenol stimulates inositol trisphosphate (IP 3) formation and cytosolic Ca 2+ ([Ca 2+] i) mobilization in rat parotid acini via a cAMP-dependent process. Atropine, a muscarinic antagonist, inhibited these isoproterenol responses without affecting isoproterenol-induced...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	FEBS letters 1989-11, Vol.258 (1), p.13-16
Hauptverfasser:	Horn, Valerie J., Baum, Bruce J., Ambudkar, Indu S.
Format:	Artikel
Sprache:	eng
Schlagworte:	acetylcholine Amylases - metabolism Animals Atropine Atropine - pharmacology Binding Sites - drug effects Biological and medical sciences Ca 2+ mobilization Ca2+ mobilization Calcium - metabolism Cell physiology Cells, Cultured Cyclic AMP Epinephrine - pharmacology Fundamental and applied biological sciences. Psychology Inositol Phosphates - metabolism Isoproterenol - antagonists & inhibitors Isoproterenol - pharmacology Molecular and cellular biology Neurotransmission Parotid Parotid Gland - drug effects Parotid Gland - metabolism Phosphatidylinositol 4,5-Diphosphate Phosphatidylinositols - metabolism Rats Receptor crosstalk Receptors, Adrenergic, beta - drug effects Receptors, Adrenergic, beta - physiology Receptors, Muscarinic - drug effects Receptors, Muscarinic - physiology signal transduction Signal Transduction - drug effects
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!