Primary hypercoagulable states in general and vascular surgery

Primary hypercoagulable states are increasingly recognized as causes of venous and arterial thromboembolism in surgical patients. Herein, we describe 10 patients with this syndrome who were diagnosed during a recent 1-year period. A family history and past medical history of thromboembolism and an u...

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Veröffentlicht in:The American journal of surgery 1989-12, Vol.158 (6), p.491-494
Hauptverfasser: Thomas, James H., Pierce, George E., Delcore, Romano, Bodensteiner, David C., Iliopolous, John I., Hermreck, Arlo S.
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container_end_page 494
container_issue 6
container_start_page 491
container_title The American journal of surgery
container_volume 158
creator Thomas, James H.
Pierce, George E.
Delcore, Romano
Bodensteiner, David C.
Iliopolous, John I.
Hermreck, Arlo S.
description Primary hypercoagulable states are increasingly recognized as causes of venous and arterial thromboembolism in surgical patients. Herein, we describe 10 patients with this syndrome who were diagnosed during a recent 1-year period. A family history and past medical history of thromboembolism and an unusual site of thrombosis are emphasized for accurate diagnosis. Although antithrombin III deficiencies were the most common abnormality found, we describe three patients with hypofibrinolytic syndromes and increased levels of tissue plasminogen activator inhibitor. The effectiveness of anticoagulation therapy in preventing recurrent thromboembolism is stressed.
doi_str_mv 10.1016/0002-9610(89)90177-3
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subjects Adolescent
Adult
Antithrombin III Deficiency
Biological and medical sciences
Female
Fibrinolysis
Humans
Intraoperative Complications
Male
Medical sciences
Plasminogen Inactivators - blood
Postoperative Complications
Protein C Deficiency
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Thrombosis - blood
Thrombosis - diagnosis
Thrombosis - etiology
Tissue Plasminogen Activator - blood
Vascular surgery: aorta, extremities, vena cava. Surgery of the lymphatic vessels
Vascular Surgical Procedures
title Primary hypercoagulable states in general and vascular surgery
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