Primary hypercoagulable states in general and vascular surgery
Primary hypercoagulable states are increasingly recognized as causes of venous and arterial thromboembolism in surgical patients. Herein, we describe 10 patients with this syndrome who were diagnosed during a recent 1-year period. A family history and past medical history of thromboembolism and an u...
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Veröffentlicht in: | The American journal of surgery 1989-12, Vol.158 (6), p.491-494 |
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container_end_page | 494 |
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container_issue | 6 |
container_start_page | 491 |
container_title | The American journal of surgery |
container_volume | 158 |
creator | Thomas, James H. Pierce, George E. Delcore, Romano Bodensteiner, David C. Iliopolous, John I. Hermreck, Arlo S. |
description | Primary hypercoagulable states are increasingly recognized as causes of venous and arterial thromboembolism in surgical patients. Herein, we describe 10 patients with this syndrome who were diagnosed during a recent 1-year period. A family history and past medical history of thromboembolism and an unusual site of thrombosis are emphasized for accurate diagnosis. Although antithrombin III deficiencies were the most common abnormality found, we describe three patients with hypofibrinolytic syndromes and increased levels of tissue plasminogen activator inhibitor. The effectiveness of anticoagulation therapy in preventing recurrent thromboembolism is stressed. |
doi_str_mv | 10.1016/0002-9610(89)90177-3 |
format | Article |
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Herein, we describe 10 patients with this syndrome who were diagnosed during a recent 1-year period. A family history and past medical history of thromboembolism and an unusual site of thrombosis are emphasized for accurate diagnosis. Although antithrombin III deficiencies were the most common abnormality found, we describe three patients with hypofibrinolytic syndromes and increased levels of tissue plasminogen activator inhibitor. 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Herein, we describe 10 patients with this syndrome who were diagnosed during a recent 1-year period. A family history and past medical history of thromboembolism and an unusual site of thrombosis are emphasized for accurate diagnosis. Although antithrombin III deficiencies were the most common abnormality found, we describe three patients with hypofibrinolytic syndromes and increased levels of tissue plasminogen activator inhibitor. The effectiveness of anticoagulation therapy in preventing recurrent thromboembolism is stressed.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Antithrombin III Deficiency</subject><subject>Biological and medical sciences</subject><subject>Female</subject><subject>Fibrinolysis</subject><subject>Humans</subject><subject>Intraoperative Complications</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Plasminogen Inactivators - blood</subject><subject>Postoperative Complications</subject><subject>Protein C Deficiency</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Thrombosis - blood</subject><subject>Thrombosis - diagnosis</subject><subject>Thrombosis - etiology</subject><subject>Tissue Plasminogen Activator - blood</subject><subject>Vascular surgery: aorta, extremities, vena cava. 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Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Thrombosis - blood</topic><topic>Thrombosis - diagnosis</topic><topic>Thrombosis - etiology</topic><topic>Tissue Plasminogen Activator - blood</topic><topic>Vascular surgery: aorta, extremities, vena cava. Surgery of the lymphatic vessels</topic><topic>Vascular Surgical Procedures</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Thomas, James H.</creatorcontrib><creatorcontrib>Pierce, George E.</creatorcontrib><creatorcontrib>Delcore, Romano</creatorcontrib><creatorcontrib>Bodensteiner, David C.</creatorcontrib><creatorcontrib>Iliopolous, John I.</creatorcontrib><creatorcontrib>Hermreck, Arlo S.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Thomas, James H.</au><au>Pierce, George E.</au><au>Delcore, Romano</au><au>Bodensteiner, David C.</au><au>Iliopolous, John I.</au><au>Hermreck, Arlo S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Primary hypercoagulable states in general and vascular surgery</atitle><jtitle>The American journal of surgery</jtitle><addtitle>Am J Surg</addtitle><date>1989-12-01</date><risdate>1989</risdate><volume>158</volume><issue>6</issue><spage>491</spage><epage>494</epage><pages>491-494</pages><issn>0002-9610</issn><eissn>1879-1883</eissn><coden>AJSUAB</coden><abstract>Primary hypercoagulable states are increasingly recognized as causes of venous and arterial thromboembolism in surgical patients. 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subjects | Adolescent Adult Antithrombin III Deficiency Biological and medical sciences Female Fibrinolysis Humans Intraoperative Complications Male Medical sciences Plasminogen Inactivators - blood Postoperative Complications Protein C Deficiency Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Thrombosis - blood Thrombosis - diagnosis Thrombosis - etiology Tissue Plasminogen Activator - blood Vascular surgery: aorta, extremities, vena cava. Surgery of the lymphatic vessels Vascular Surgical Procedures |
title | Primary hypercoagulable states in general and vascular surgery |
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