NMR investigation on the structure and conformation of 3′-azido-2′,3′-dideoxyribosylthymine (AZT), an inhibitor of the HIV (AIDS virus)

1H and 13C NMR study of 3′-azido-2′,3′-dideoxyribosylthymine (AZT), an inhibitor of HIV (human immunodeficiency virus) replication, has been undertaken. Modified Karplus relations have been used to obtain the molecular structure from the indirect coupling constants. NMR results are consistent with a...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Biochemical and biophysical research communications 1989-11, Vol.164 (3), p.1086-1092
Hauptverfasser:	Swapna, G.V.T., Jagannadh, B., Gurjar, M.K., Kunwar, A.C.
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV human immunodeficiency virus Hydrogen Magnetic Resonance Spectroscopy - methods Molecular Conformation Molecular Structure X-Ray Diffraction Zidovudine - chemical synthesis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!