Expression of different 17beta-hydroxysteroid dehydrogenase types and their activities in human prostate cancer cells

The 17beta-hydroxysteroid dehydrogenase (17betaHSD) enzyme system governs important redox reactions at the C17 position of steroid hormones. Different 17betaHSD types (no. 1-4) have been identified to date in peripheral human tissues, such as placenta, testis, and breast. However, there is little in...

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Veröffentlicht in:	Endocrinology (Philadelphia) 1997-11, Vol.138 (11), p.4876-4882
Hauptverfasser:	Castagnetta, L A, Carruba, G, Traina, A, Granata, O M, Markus, M, Pavone-Macaluso, M, Blomquist, C H, Adamski, J
Format:	Artikel
Sprache:	eng
Schlagworte:	17-Hydroxysteroid Dehydrogenases - genetics 17-Hydroxysteroid Dehydrogenases - metabolism Estradiol - metabolism Humans Isoenzymes - genetics Isoenzymes - metabolism Male Oxidation-Reduction Prostatic Neoplasms - metabolism Prostatic Neoplasms - pathology RNA, Messenger - metabolism Subcellular Fractions - metabolism Testosterone - metabolism Tumor Cells, Cultured
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