Enhancement of retroviral production from packaging cell lines expressing the human immunodeficiency type 1 VPU gene

The HIV-1 Vpu protein stimulates virus production by enhancing the release of viral particles from infected cells. Interestingly, Vpu was also shown to enhance the release of capsids produced by gag gene contructs of other retroviruses that lack a Vpu-like activity. To investigate the effect of Vpu...

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Veröffentlicht in:Gene therapy 1997-08, Vol.4 (8), p.868-874
Hauptverfasser: Kobinger, G P, Mouland, A J, Lalonde, J P, Forget, J, Cohen, E A
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Sprache:eng
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