Characterization of PPD‐Specific T‐Cell Lines Generated in Type I (Insulin‐Dependent) Diabetic and Healthy Individuals

The particular susceptibility to insulin‐dependent diabetes mellitus (IDDM) conferred by HLA‐DR3,4 heterozygosity has been suggested to be an effect of transcomplementation of HLA class II molecules. To test this hypothesis of special IDDM‐specific hybrid determinants and to evaluate the T‐cell repe...

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Veröffentlicht in:	Scandinavian journal of immunology 1989-11, Vol.30 (5), p.615-629
Hauptverfasser:	Mølvig, J., MCDEVITT, G. SØNDERSTRUP, THOMSEN, M., BOSMANN, B., BLANGERO, C., PREVAL, C., BAEK, L., NERUP, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigen-Presenting Cells - physiology Biological and medical sciences Cell Line Diabetes Mellitus, Type 1 - immunology Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance HLA-DR Antigens - analysis Humans Lipopolysaccharides - pharmacology Lymphocyte Activation - drug effects Medical sciences T-Lymphocytes - immunology Tuberculin - immunology
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