A luminescence probe for metallothionein in liver tissue: emission intensity measured directly from copper metallothionein induced in rat liver

We report the first use of an emission probe based on the Cu(I)-thiolate chromophore, for the direct observation of copper metallothionein located in samples of rat liver. Elevated synthesis of Cu-MT in the rat liver was induced by subcutaneous injections of a series of aqueous CuCl 2 solutions cont...

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Veröffentlicht in:	FEBS Letters 1989-11, Vol.257 (2), p.283-286
Hauptverfasser:	Stillman, Martin J., Gasyna, Zbigniew, Zelazowski, Andrzej J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Animals Biological and medical sciences Copper - analysis Copper - metabolism Copper binding Fundamental and applied biological sciences. Psychology Hepatolenticular Degeneration Humans Light emission Liver - analysis Luminescence Metalloproteins Metallothionein Metallothionein - analysis Other metalloproteins Proteins Rat liver tissue Rats Spectrum Analysis Wilson's disease
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