Mapping epitopes to distinct regions of the extracellular domain of endoglin using bacterially expressed recombinant fragments

Endoglin (CD 105) is a homodimeric cell surface component of the TGFß1 receptor complex, which is expressed at high levels on vascular endothelium and at lower levels on activated monocytes. It is also the target gene for the dominantly inherited vascular disorder hereditary hemorrhagic telangiectas...

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