Proliferation of the human colon carcinoma cell line HT29: autocrine growth and deregulated expression of the c-myc oncogene

Human colon adenocarcinoma cell (line HT29) are able to proliferate in a defined (serum-free) medium containing no added growth factors; in such conditions, their doubling time is 3 to 4 days (on serum-coated dishes) or 2 to 3 days (on an autologous extracellular matrix) compared with 1 day in the p...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1989-12, Vol.49 (23), p.6566-6571
Hauptverfasser:	FORGUE-LAFITTE, M.-E, COUDRAY, A.-M, BREANT, B, MESTER, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blotting, Northern Blotting, Southern carcinoma Carcinoma - pathology Cell Differentiation Cell Division - drug effects colon Colonic Neoplasms - pathology Culture Media Gastroenterology. Liver. Pancreas. Abdomen gene expression Gene Expression Regulation, Neoplastic Growth Substances - physiology Medical sciences Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins c-myc Proto-Oncogenes Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Suramin - pharmacology Transcription, Genetic Tumor Cells, Cultured Tumors
Online-Zugang:	Volltext
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