Aged and non-aged pyrenebutyl-containing organophosphoryl conjugates of chymotrypsin: Preparation and comparison by 31P-NMR spectroscopy

Homologous pairs of non-aged and aged pyrene-containing phosphoryl conjugates of chymotrypsin were prepared in order to characterize by NMR and optical spectroscopy putative differences in the conformation of non-aged and aged organophosphoryl conjugates of serine hydrolases. Pyrenebutyl-O-P(O)(OC 2...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemical pharmacology 1989-10, Vol.38 (19), p.3157-3168
Hauptverfasser:	Grunwald, Jacob, Segall, Yoffi, Shirin, Ezra, Waysbort, Daniel, Steinberg, Nitza, Silman, Israel, Ashani, Yacov
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Biological and medical sciences Chymotrypsin - analysis Chymotrypsin - antagonists & inhibitors Chymotrypsin - chemical synthesis Dealkylation Enzyme Activation Enzymes and enzyme inhibitors Fluorescence Fundamental and applied biological sciences. Psychology Hydrolases Magnetic Resonance Spectroscopy Organophosphorus Compounds - analysis Organophosphorus Compounds - chemical synthesis Organophosphorus Compounds - pharmacology Protein Conformation Pyrenes - analysis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!