The important role of left ventricular relaxation and left atrial pressure in the left ventricular filling velocity profile
To evaluate the determinants of left ventricular filling, left ventricular filling velocity was measured by pulsed Doppler flowmetry during catheterization of the right and left sides of the heart in 37 patients with cardiac disease before and during leg elevation. During leg elevation, despite no s...
Gespeichert in:
| Veröffentlicht in: | The American heart journal 1989-11, Vol.118 (5), p.954-962 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 962 |
|---|---|
| container_issue | 5 |
| container_start_page | 954 |
| container_title | The American heart journal |
| container_volume | 118 |
| creator | Takagi, Shigehito Yokota, Mitsuhiro Iwase, Masatsugu Yoshida, Junshi Hayashi, Hiroshi Sotobata, Iwao Koide, Masafumi Saito, Hidehiko |
| description | To evaluate the determinants of left ventricular filling, left ventricular filling velocity was measured by pulsed Doppler flowmetry during catheterization of the right and left sides of the heart in 37 patients with cardiac disease before and during leg elevation. During leg elevation, despite no significant change in the time constant of isovolumic relaxation (T), the peak rapid filling velocity (PVRF) increased in association with an increase in pulmonary wedge pressure (PWP), but the peak atrial filling velocity was unchanged. The PVRF correlated with the pulmonary wedge V wave — left ventricular minimum pressure difference (
r = 0.68) and in multivariate regression with both T and mean PWP (R = 0.73). These results indicate that left ventricular filling is determined by both left ventricular relaxation and left atrial pressure and that an increase in left atrial pressure changes the left ventricular filling velocity profile in a manner that mimics the pattern with normal diastolic function. |
| doi_str_mv | 10.1016/0002-8703(89)90230-5 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_79320947</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>0002870389902305</els_id><sourcerecordid>79320947</sourcerecordid><originalsourceid>FETCH-LOGICAL-c357t-4a726317f96462207ec35f08e76f294a1f8eef1bf24a2424950c6939898bc64c3</originalsourceid><addsrcrecordid>eNp9UEtLAzEQDqJoffwDhZxED6vZbJrHRRDxBYIXPYc0nWgk3dQkWxT_vKktXgRPw3yvYT6EDlty1pKWnxNCaCMF6U6kOlWEdqQZb6BRS5RouGBsE41-JTtoN-e3unIq-Tbaplx2XKkR-np6Bexn85iK6QtOMQCODgdwBS-gL8nbIZiEEwTzYYqPPTb9dMWbypqA5wlyHlKN6XGpaX-8zofg-5eKhWh9-ayOWDHYR1vOhAwH67mHnm-un67umofH2_ury4fGdmNRGmYE5V0rnOKMU0oEVNwRCYI7qphpnQRw7cRRZiijTI2J5apTUsmJ5cx2e-h4lVvvvg-Qi575bCEE00Mcshaqo0QxUYVsJbQp5pzA6XnyM5M-dUv0snO9LFQvC9VS6Z_O9bjajtb5w2QG01_TuuTKX6x4qE8uPCSdrYfewtQnsEVPo___wDf7zZI1</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>79320947</pqid></control><display><type>article</type><title>The important role of left ventricular relaxation and left atrial pressure in the left ventricular filling velocity profile</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><creator>Takagi, Shigehito ; Yokota, Mitsuhiro ; Iwase, Masatsugu ; Yoshida, Junshi ; Hayashi, Hiroshi ; Sotobata, Iwao ; Koide, Masafumi ; Saito, Hidehiko</creator><creatorcontrib>Takagi, Shigehito ; Yokota, Mitsuhiro ; Iwase, Masatsugu ; Yoshida, Junshi ; Hayashi, Hiroshi ; Sotobata, Iwao ; Koide, Masafumi ; Saito, Hidehiko</creatorcontrib><description>To evaluate the determinants of left ventricular filling, left ventricular filling velocity was measured by pulsed Doppler flowmetry during catheterization of the right and left sides of the heart in 37 patients with cardiac disease before and during leg elevation. During leg elevation, despite no significant change in the time constant of isovolumic relaxation (T), the peak rapid filling velocity (PVRF) increased in association with an increase in pulmonary wedge pressure (PWP), but the peak atrial filling velocity was unchanged. The PVRF correlated with the pulmonary wedge V wave — left ventricular minimum pressure difference (
r = 0.68) and in multivariate regression with both T and mean PWP (R = 0.73). These results indicate that left ventricular filling is determined by both left ventricular relaxation and left atrial pressure and that an increase in left atrial pressure changes the left ventricular filling velocity profile in a manner that mimics the pattern with normal diastolic function.</description><identifier>ISSN: 0002-8703</identifier><identifier>EISSN: 1097-6744</identifier><identifier>DOI: 10.1016/0002-8703(89)90230-5</identifier><identifier>PMID: 2683699</identifier><language>eng</language><publisher>United States: Mosby, Inc</publisher><subject>Adult ; Blood Flow Velocity ; Blood Pressure ; Coronary Circulation ; Female ; Heart - physiopathology ; Heart Atria ; Heart Diseases - physiopathology ; Heart Ventricles ; Humans ; Leg - physiology ; Male ; Middle Aged ; Mitral Valve - physiopathology ; Multivariate Analysis ; Myocardial Contraction ; Posture ; Ultrasonography</subject><ispartof>The American heart journal, 1989-11, Vol.118 (5), p.954-962</ispartof><rights>1989</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c357t-4a726317f96462207ec35f08e76f294a1f8eef1bf24a2424950c6939898bc64c3</citedby><cites>FETCH-LOGICAL-c357t-4a726317f96462207ec35f08e76f294a1f8eef1bf24a2424950c6939898bc64c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0002-8703(89)90230-5$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2683699$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Takagi, Shigehito</creatorcontrib><creatorcontrib>Yokota, Mitsuhiro</creatorcontrib><creatorcontrib>Iwase, Masatsugu</creatorcontrib><creatorcontrib>Yoshida, Junshi</creatorcontrib><creatorcontrib>Hayashi, Hiroshi</creatorcontrib><creatorcontrib>Sotobata, Iwao</creatorcontrib><creatorcontrib>Koide, Masafumi</creatorcontrib><creatorcontrib>Saito, Hidehiko</creatorcontrib><title>The important role of left ventricular relaxation and left atrial pressure in the left ventricular filling velocity profile</title><title>The American heart journal</title><addtitle>Am Heart J</addtitle><description>To evaluate the determinants of left ventricular filling, left ventricular filling velocity was measured by pulsed Doppler flowmetry during catheterization of the right and left sides of the heart in 37 patients with cardiac disease before and during leg elevation. During leg elevation, despite no significant change in the time constant of isovolumic relaxation (T), the peak rapid filling velocity (PVRF) increased in association with an increase in pulmonary wedge pressure (PWP), but the peak atrial filling velocity was unchanged. The PVRF correlated with the pulmonary wedge V wave — left ventricular minimum pressure difference (
r = 0.68) and in multivariate regression with both T and mean PWP (R = 0.73). These results indicate that left ventricular filling is determined by both left ventricular relaxation and left atrial pressure and that an increase in left atrial pressure changes the left ventricular filling velocity profile in a manner that mimics the pattern with normal diastolic function.</description><subject>Adult</subject><subject>Blood Flow Velocity</subject><subject>Blood Pressure</subject><subject>Coronary Circulation</subject><subject>Female</subject><subject>Heart - physiopathology</subject><subject>Heart Atria</subject><subject>Heart Diseases - physiopathology</subject><subject>Heart Ventricles</subject><subject>Humans</subject><subject>Leg - physiology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Mitral Valve - physiopathology</subject><subject>Multivariate Analysis</subject><subject>Myocardial Contraction</subject><subject>Posture</subject><subject>Ultrasonography</subject><issn>0002-8703</issn><issn>1097-6744</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9UEtLAzEQDqJoffwDhZxED6vZbJrHRRDxBYIXPYc0nWgk3dQkWxT_vKktXgRPw3yvYT6EDlty1pKWnxNCaCMF6U6kOlWEdqQZb6BRS5RouGBsE41-JTtoN-e3unIq-Tbaplx2XKkR-np6Bexn85iK6QtOMQCODgdwBS-gL8nbIZiEEwTzYYqPPTb9dMWbypqA5wlyHlKN6XGpaX-8zofg-5eKhWh9-ayOWDHYR1vOhAwH67mHnm-un67umofH2_ury4fGdmNRGmYE5V0rnOKMU0oEVNwRCYI7qphpnQRw7cRRZiijTI2J5apTUsmJ5cx2e-h4lVvvvg-Qi575bCEE00Mcshaqo0QxUYVsJbQp5pzA6XnyM5M-dUv0snO9LFQvC9VS6Z_O9bjajtb5w2QG01_TuuTKX6x4qE8uPCSdrYfewtQnsEVPo___wDf7zZI1</recordid><startdate>19891101</startdate><enddate>19891101</enddate><creator>Takagi, Shigehito</creator><creator>Yokota, Mitsuhiro</creator><creator>Iwase, Masatsugu</creator><creator>Yoshida, Junshi</creator><creator>Hayashi, Hiroshi</creator><creator>Sotobata, Iwao</creator><creator>Koide, Masafumi</creator><creator>Saito, Hidehiko</creator><general>Mosby, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19891101</creationdate><title>The important role of left ventricular relaxation and left atrial pressure in the left ventricular filling velocity profile</title><author>Takagi, Shigehito ; Yokota, Mitsuhiro ; Iwase, Masatsugu ; Yoshida, Junshi ; Hayashi, Hiroshi ; Sotobata, Iwao ; Koide, Masafumi ; Saito, Hidehiko</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-4a726317f96462207ec35f08e76f294a1f8eef1bf24a2424950c6939898bc64c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>Adult</topic><topic>Blood Flow Velocity</topic><topic>Blood Pressure</topic><topic>Coronary Circulation</topic><topic>Female</topic><topic>Heart - physiopathology</topic><topic>Heart Atria</topic><topic>Heart Diseases - physiopathology</topic><topic>Heart Ventricles</topic><topic>Humans</topic><topic>Leg - physiology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Mitral Valve - physiopathology</topic><topic>Multivariate Analysis</topic><topic>Myocardial Contraction</topic><topic>Posture</topic><topic>Ultrasonography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Takagi, Shigehito</creatorcontrib><creatorcontrib>Yokota, Mitsuhiro</creatorcontrib><creatorcontrib>Iwase, Masatsugu</creatorcontrib><creatorcontrib>Yoshida, Junshi</creatorcontrib><creatorcontrib>Hayashi, Hiroshi</creatorcontrib><creatorcontrib>Sotobata, Iwao</creatorcontrib><creatorcontrib>Koide, Masafumi</creatorcontrib><creatorcontrib>Saito, Hidehiko</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American heart journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Takagi, Shigehito</au><au>Yokota, Mitsuhiro</au><au>Iwase, Masatsugu</au><au>Yoshida, Junshi</au><au>Hayashi, Hiroshi</au><au>Sotobata, Iwao</au><au>Koide, Masafumi</au><au>Saito, Hidehiko</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The important role of left ventricular relaxation and left atrial pressure in the left ventricular filling velocity profile</atitle><jtitle>The American heart journal</jtitle><addtitle>Am Heart J</addtitle><date>1989-11-01</date><risdate>1989</risdate><volume>118</volume><issue>5</issue><spage>954</spage><epage>962</epage><pages>954-962</pages><issn>0002-8703</issn><eissn>1097-6744</eissn><abstract>To evaluate the determinants of left ventricular filling, left ventricular filling velocity was measured by pulsed Doppler flowmetry during catheterization of the right and left sides of the heart in 37 patients with cardiac disease before and during leg elevation. During leg elevation, despite no significant change in the time constant of isovolumic relaxation (T), the peak rapid filling velocity (PVRF) increased in association with an increase in pulmonary wedge pressure (PWP), but the peak atrial filling velocity was unchanged. The PVRF correlated with the pulmonary wedge V wave — left ventricular minimum pressure difference (
r = 0.68) and in multivariate regression with both T and mean PWP (R = 0.73). These results indicate that left ventricular filling is determined by both left ventricular relaxation and left atrial pressure and that an increase in left atrial pressure changes the left ventricular filling velocity profile in a manner that mimics the pattern with normal diastolic function.</abstract><cop>United States</cop><pub>Mosby, Inc</pub><pmid>2683699</pmid><doi>10.1016/0002-8703(89)90230-5</doi><tpages>9</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0002-8703 |
| ispartof | The American heart journal, 1989-11, Vol.118 (5), p.954-962 |
| issn | 0002-8703 1097-6744 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_79320947 |
| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Adult Blood Flow Velocity Blood Pressure Coronary Circulation Female Heart - physiopathology Heart Atria Heart Diseases - physiopathology Heart Ventricles Humans Leg - physiology Male Middle Aged Mitral Valve - physiopathology Multivariate Analysis Myocardial Contraction Posture Ultrasonography |
| title | The important role of left ventricular relaxation and left atrial pressure in the left ventricular filling velocity profile |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T03%3A13%3A03IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20important%20role%20of%20left%20ventricular%20relaxation%20and%20left%20atrial%20pressure%20in%20the%20left%20ventricular%20filling%20velocity%20profile&rft.jtitle=The%20American%20heart%20journal&rft.au=Takagi,%20Shigehito&rft.date=1989-11-01&rft.volume=118&rft.issue=5&rft.spage=954&rft.epage=962&rft.pages=954-962&rft.issn=0002-8703&rft.eissn=1097-6744&rft_id=info:doi/10.1016/0002-8703(89)90230-5&rft_dat=%3Cproquest_cross%3E79320947%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=79320947&rft_id=info:pmid/2683699&rft_els_id=0002870389902305&rfr_iscdi=true |