Hydroxyl Radical Generation in Oxygen-treated Infants

Because the hydroxyl radical is capable of oxidizing phenylalanine to O-tyrosine, we sought to determine whether increased levels of O-tyrosine are found in urine of infants treated with supplemental oxygen. A total of 39 consecutively admitted neonates to an intensive care unit were included. Twent...

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Veröffentlicht in:	Pediatrics (Evanston) 1997-10, Vol.100 (4), p.700-704
Hauptverfasser:	Lubec, Gert, Widness, John A, Hayde, Michael, Menzel, Daniel, Pollak, Arnold
Format:	Artikel
Sprache:	eng
Schlagworte:	Active oxygen Active oxygen in the body Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Apgar Score Babies Biological and medical sciences Body fluids Children Dose-Response Relationship, Drug Emergency and intensive care: neonates and children. Prematurity. Sudden death Free radicals Free radicals (Chemistry) Humans Hydroxyl Radical - metabolism Infant, Newborn - metabolism Infant, Newborn - urine Infant, Newborn, Diseases - metabolism Infant, Newborn, Diseases - therapy Infant, Newborn, Diseases - urine Intensive care medicine Measurement Medical sciences Oxygen Oxygen - administration & dosage Oxygen - metabolism Oxygen Inhalation Therapy Oxygen therapy Oxygen therapy for children Pediatrics Phenylalanine - metabolism Phenylalanine - urine Physiological aspects Regression Analysis Tyrosine Tyrosine - urine Tyrosine in the body
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