Left Main Coronary Artery Compression During Primary Pulmonary Hypertension
Primary pulmonary hypertension (PPH) is often associated with angina-like chest pain, the mechanism of which is controversial. A 37-year-old woman with severe PPH and angina had transient ischemic ECG changes and reversible anterior perfusion defect on 201thallium scintigraphy. Coronary angiography...
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| Veröffentlicht in: | Chest 1997-09, Vol.112 (3), p.842-843 |
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| creator | Patrat, Jean-Frederic Jondeau, Guillaume Dubourg, Olivier Rigaud, Michel Bourdarias, Jean-Pierre Lacombe, Pascal Gandjbakhch, Iradj |
| description | Primary pulmonary hypertension (PPH) is often associated with angina-like chest pain, the mechanism of which is controversial. A 37-year-old woman with severe PPH and angina had transient ischemic ECG changes and reversible anterior perfusion defect on 201thallium scintigraphy. Coronary angiography revealed severe stenosis of the left main coronary artery (LMCA) and otherwise normal vessels. After heart-lung transplantation, examination of the explanted heart showed normal coronary arteries. Compression of the LMCA by the dilated pulmonary artery trunk was responsible for myocardial ischemia. This mechanism should be considered in patients with PPH and angina and might contribute to the high sudden death rate. |
| doi_str_mv | 10.1378/chest.112.3.842 |
| format | Article |
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A 37-year-old woman with severe PPH and angina had transient ischemic ECG changes and reversible anterior perfusion defect on 201thallium scintigraphy. Coronary angiography revealed severe stenosis of the left main coronary artery (LMCA) and otherwise normal vessels. After heart-lung transplantation, examination of the explanted heart showed normal coronary arteries. Compression of the LMCA by the dilated pulmonary artery trunk was responsible for myocardial ischemia. This mechanism should be considered in patients with PPH and angina and might contribute to the high sudden death rate.</description><identifier>ISSN: 0012-3692</identifier><identifier>EISSN: 1931-3543</identifier><identifier>DOI: 10.1378/chest.112.3.842</identifier><identifier>PMID: 9315824</identifier><identifier>CODEN: CHETBF</identifier><language>eng</language><publisher>Northbrook, IL: Elsevier Inc</publisher><subject>Adult ; angina ; Angina Pectoris - etiology ; Arterial occlusions ; Biological and medical sciences ; chest pain ; Complications and side effects ; Constriction, Pathologic - diagnostic imaging ; Constriction, Pathologic - etiology ; Constriction, Pathologic - surgery ; Coronary Angiography ; Coronary arteries ; Coronary Disease - diagnostic imaging ; Coronary Disease - etiology ; Coronary Disease - surgery ; Death, Sudden, Cardiac - etiology ; Dilatation, Pathologic - pathology ; Electrocardiography ; Female ; Heart-Lung Transplantation ; Humans ; Hypertension, Pulmonary - complications ; Hypertension, Pulmonary - pathology ; Hypertension, Pulmonary - surgery ; left coronary artery ; Medical sciences ; Myocardial Ischemia - etiology ; Pneumology ; primary pulmonary hypertension ; Pulmonary Artery - pathology ; Pulmonary hypertension ; Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases ; Radionuclide Imaging ; Radiopharmaceuticals ; Thallium Radioisotopes</subject><ispartof>Chest, 1997-09, Vol.112 (3), p.842-843</ispartof><rights>1997 The American College of Chest Physicians</rights><rights>1997 INIST-CNRS</rights><rights>COPYRIGHT 1997 Elsevier B.V.</rights><rights>Copyright American College of Chest Physicians Sep 1997</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c540t-e767ac93992772949153a5ac6d5dc8bcd18531e3424e236836c50268a8141c793</citedby><cites>FETCH-LOGICAL-c540t-e767ac93992772949153a5ac6d5dc8bcd18531e3424e236836c50268a8141c793</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2826652$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9315824$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Patrat, Jean-Frederic</creatorcontrib><creatorcontrib>Jondeau, Guillaume</creatorcontrib><creatorcontrib>Dubourg, Olivier</creatorcontrib><creatorcontrib>Rigaud, Michel</creatorcontrib><creatorcontrib>Bourdarias, Jean-Pierre</creatorcontrib><creatorcontrib>Lacombe, Pascal</creatorcontrib><creatorcontrib>Gandjbakhch, Iradj</creatorcontrib><title>Left Main Coronary Artery Compression During Primary Pulmonary Hypertension</title><title>Chest</title><addtitle>Chest</addtitle><description>Primary pulmonary hypertension (PPH) is often associated with angina-like chest pain, the mechanism of which is controversial. A 37-year-old woman with severe PPH and angina had transient ischemic ECG changes and reversible anterior perfusion defect on 201thallium scintigraphy. Coronary angiography revealed severe stenosis of the left main coronary artery (LMCA) and otherwise normal vessels. After heart-lung transplantation, examination of the explanted heart showed normal coronary arteries. Compression of the LMCA by the dilated pulmonary artery trunk was responsible for myocardial ischemia. This mechanism should be considered in patients with PPH and angina and might contribute to the high sudden death rate.</description><subject>Adult</subject><subject>angina</subject><subject>Angina Pectoris - etiology</subject><subject>Arterial occlusions</subject><subject>Biological and medical sciences</subject><subject>chest pain</subject><subject>Complications and side effects</subject><subject>Constriction, Pathologic - diagnostic imaging</subject><subject>Constriction, Pathologic - etiology</subject><subject>Constriction, Pathologic - surgery</subject><subject>Coronary Angiography</subject><subject>Coronary arteries</subject><subject>Coronary Disease - diagnostic imaging</subject><subject>Coronary Disease - etiology</subject><subject>Coronary Disease - surgery</subject><subject>Death, Sudden, Cardiac - etiology</subject><subject>Dilatation, Pathologic - pathology</subject><subject>Electrocardiography</subject><subject>Female</subject><subject>Heart-Lung Transplantation</subject><subject>Humans</subject><subject>Hypertension, Pulmonary - complications</subject><subject>Hypertension, Pulmonary - pathology</subject><subject>Hypertension, Pulmonary - surgery</subject><subject>left coronary artery</subject><subject>Medical sciences</subject><subject>Myocardial Ischemia - etiology</subject><subject>Pneumology</subject><subject>primary pulmonary hypertension</subject><subject>Pulmonary Artery - pathology</subject><subject>Pulmonary hypertension</subject><subject>Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases</subject><subject>Radionuclide Imaging</subject><subject>Radiopharmaceuticals</subject><subject>Thallium Radioisotopes</subject><issn>0012-3692</issn><issn>1931-3543</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kctv1DAQhy1EVZbCmRNShBAnsvUjD_u42gKtWEQPcLZcZ7LrKrEXO6Hqf88sidoKLfJh5Jlvnj9C3jC6ZKKW53YHaVgyxpdiKQv-jCyYEiwXZSGekwWljOeiUvwFeZnSLcU_U9UpOUWmlLxYkK8baIfsm3E-W4cYvIn32SoOgGYd-n2ElFzw2cUYnd9m19H1B-J67PqJvbzfA-L-QL0iJ63pErye7Rn5-fnTj_Vlvvn-5Wq92uS2LOiQQ13VxiqhFK9rrgrFSmFKY6umbKy8sQ2TpWAgCl4AF5UUlS0pr6SRrGC2VuKMfJjq7mP4NeL-unfJQtcZD2FMGhGqmGAIvvsHvA1j9Dib5pQWeClRP0Jb04F2vg1DNPZQUa-YkoJJRhH6eATagodouuChdeh-iudHcHwN9M4e488n3saQUoRW76dLa0b1QWf9V2eNOmuhUWfMeDuvNt700Dzws7AYfz_HTbKma6Px1qUHjEteVSV_bLxz292di6BTb7oOi4qp5Xywp43VlAGo8G8HUSfrwFtoMNsOugnuv0P_AblA0h4</recordid><startdate>19970901</startdate><enddate>19970901</enddate><creator>Patrat, Jean-Frederic</creator><creator>Jondeau, Guillaume</creator><creator>Dubourg, Olivier</creator><creator>Rigaud, Michel</creator><creator>Bourdarias, Jean-Pierre</creator><creator>Lacombe, Pascal</creator><creator>Gandjbakhch, Iradj</creator><general>Elsevier Inc</general><general>American College of Chest Physicians</general><general>Elsevier B.V</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>19970901</creationdate><title>Left Main Coronary Artery Compression During Primary Pulmonary Hypertension</title><author>Patrat, Jean-Frederic ; Jondeau, Guillaume ; Dubourg, Olivier ; Rigaud, Michel ; Bourdarias, Jean-Pierre ; Lacombe, Pascal ; Gandjbakhch, Iradj</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c540t-e767ac93992772949153a5ac6d5dc8bcd18531e3424e236836c50268a8141c793</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Adult</topic><topic>angina</topic><topic>Angina Pectoris - etiology</topic><topic>Arterial occlusions</topic><topic>Biological and medical sciences</topic><topic>chest pain</topic><topic>Complications and side effects</topic><topic>Constriction, Pathologic - diagnostic imaging</topic><topic>Constriction, Pathologic - etiology</topic><topic>Constriction, Pathologic - surgery</topic><topic>Coronary Angiography</topic><topic>Coronary arteries</topic><topic>Coronary Disease - diagnostic imaging</topic><topic>Coronary Disease - etiology</topic><topic>Coronary Disease - surgery</topic><topic>Death, Sudden, Cardiac - etiology</topic><topic>Dilatation, Pathologic - pathology</topic><topic>Electrocardiography</topic><topic>Female</topic><topic>Heart-Lung Transplantation</topic><topic>Humans</topic><topic>Hypertension, Pulmonary - complications</topic><topic>Hypertension, Pulmonary - pathology</topic><topic>Hypertension, Pulmonary - surgery</topic><topic>left coronary artery</topic><topic>Medical sciences</topic><topic>Myocardial Ischemia - etiology</topic><topic>Pneumology</topic><topic>primary pulmonary hypertension</topic><topic>Pulmonary Artery - pathology</topic><topic>Pulmonary hypertension</topic><topic>Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases</topic><topic>Radionuclide Imaging</topic><topic>Radiopharmaceuticals</topic><topic>Thallium Radioisotopes</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Patrat, Jean-Frederic</creatorcontrib><creatorcontrib>Jondeau, Guillaume</creatorcontrib><creatorcontrib>Dubourg, Olivier</creatorcontrib><creatorcontrib>Rigaud, Michel</creatorcontrib><creatorcontrib>Bourdarias, Jean-Pierre</creatorcontrib><creatorcontrib>Lacombe, Pascal</creatorcontrib><creatorcontrib>Gandjbakhch, Iradj</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Proquest Nursing & Allied Health Source</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Chest</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Patrat, Jean-Frederic</au><au>Jondeau, Guillaume</au><au>Dubourg, Olivier</au><au>Rigaud, Michel</au><au>Bourdarias, Jean-Pierre</au><au>Lacombe, Pascal</au><au>Gandjbakhch, Iradj</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Left Main Coronary Artery Compression During Primary Pulmonary Hypertension</atitle><jtitle>Chest</jtitle><addtitle>Chest</addtitle><date>1997-09-01</date><risdate>1997</risdate><volume>112</volume><issue>3</issue><spage>842</spage><epage>843</epage><pages>842-843</pages><issn>0012-3692</issn><eissn>1931-3543</eissn><coden>CHETBF</coden><abstract>Primary pulmonary hypertension (PPH) is often associated with angina-like chest pain, the mechanism of which is controversial. A 37-year-old woman with severe PPH and angina had transient ischemic ECG changes and reversible anterior perfusion defect on 201thallium scintigraphy. Coronary angiography revealed severe stenosis of the left main coronary artery (LMCA) and otherwise normal vessels. After heart-lung transplantation, examination of the explanted heart showed normal coronary arteries. Compression of the LMCA by the dilated pulmonary artery trunk was responsible for myocardial ischemia. This mechanism should be considered in patients with PPH and angina and might contribute to the high sudden death rate.</abstract><cop>Northbrook, IL</cop><pub>Elsevier Inc</pub><pmid>9315824</pmid><doi>10.1378/chest.112.3.842</doi><tpages>2</tpages></addata></record> |
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| subjects | Adult angina Angina Pectoris - etiology Arterial occlusions Biological and medical sciences chest pain Complications and side effects Constriction, Pathologic - diagnostic imaging Constriction, Pathologic - etiology Constriction, Pathologic - surgery Coronary Angiography Coronary arteries Coronary Disease - diagnostic imaging Coronary Disease - etiology Coronary Disease - surgery Death, Sudden, Cardiac - etiology Dilatation, Pathologic - pathology Electrocardiography Female Heart-Lung Transplantation Humans Hypertension, Pulmonary - complications Hypertension, Pulmonary - pathology Hypertension, Pulmonary - surgery left coronary artery Medical sciences Myocardial Ischemia - etiology Pneumology primary pulmonary hypertension Pulmonary Artery - pathology Pulmonary hypertension Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases Radionuclide Imaging Radiopharmaceuticals Thallium Radioisotopes |
| title | Left Main Coronary Artery Compression During Primary Pulmonary Hypertension |
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