Localization of T and B cell stimulating domains of the immunodominant 33-kDa protein of Onchocerca volvulus (Ov33)

The localization of T and B cell epitopes on a well characterized 33-kDa protein of the filarial nematode Onchocerca volvulus (Ov33) was studied using peripheral blood mononuclear cells (PBMC) and sera from a total of 52 onchocerciasis patients with the generalized form of infection. A proportion of...

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Veröffentlicht in:	Clinical immunology and immunopathology 1997-10, Vol.85 (1), p.56-66
Hauptverfasser:	POGONKA, T, BRATTIG, N, NDE, P. N, ADAM, R, SEEBER, F, ZIPFEL, P. F, TITANJI, V. P. K, LUCIUS, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Amino Acid Sequence Animals Antibodies, Helminth - blood Antigens, Helminth - chemistry Antigens, Helminth - genetics B-Lymphocytes - immunology Biological and medical sciences Diseases caused by nematodes Female Filariases Helminth Proteins - chemistry Helminth Proteins - genetics Helminth Proteins - immunology Helminthic diseases Humans Immunodominant Epitopes - chemistry Immunodominant Epitopes - genetics In Vitro Techniques Infectious diseases Lymphocyte Activation Male Medical sciences Middle Aged Molecular Sequence Data Molecular Weight Onchocerca volvulus - genetics Onchocerca volvulus - immunology Onchocerciasis - immunology Onchocercosis Parasitic diseases Recombinant Fusion Proteins - chemistry Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - immunology T-Lymphocytes - immunology
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