Nicotine inhibits slowly inactivating K+ currents in rat cultured striatal neurons

As shown on cultured striatal neurons recorded in whole-cell configuration, both acetylcholine (in the presence of atropine) and nicotine reduced voltage-dependent outward currents. Although, at early postnatal ages, outward currents in these cells are mainly carried by rapidly and slowly inactivati...

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Veröffentlicht in:	Pflügers Archiv 1997-09, Vol.434 (5), p.642-645
Hauptverfasser:	Hamon, B, Glowinski, J, Giaume, C
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine - pharmacology Animals Cells, Cultured Corpus Striatum - cytology Corpus Striatum - drug effects Corpus Striatum - physiology Dihydro-beta-Erythroidine - pharmacology Electric Conductivity Neurons - drug effects Neurons - physiology Nicotine Nicotine - pharmacology Nicotinic Agonists - pharmacology Nicotinic Antagonists - pharmacology Potassium - antagonists & inhibitors Potassium - physiology Rats - embryology Rats, Sprague-Dawley
Online-Zugang:	Volltext
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