COMPARISON OF PULMONARY DEFENSE MECHANISMS IN ROCKY MOUNTAIN BIGHORN (OVIS CANADENSIS CANADENSIS) AND DOMESTIC SHEEP
Alveolar macrophages were obtained from Rocky Mountain bighorn sheep (Ovis canadensis canadensis) and domestic sheep for the purpose of comparing pulmonary host defense mechanisms in the two species. Specific variables studied included (1) characterization of the cell types present in the lung, (2)...
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| Veröffentlicht in: | Journal of wildlife diseases 1989-10, Vol.25 (4), p.514-520 |
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| creator | Silflow, Ronald M Foreyt, William J Taylor, Stephen M Laegreid, William W Liggitt, H. Denny Leid, R. Wes |
| description | Alveolar macrophages were obtained from Rocky Mountain bighorn sheep (Ovis canadensis canadensis) and domestic sheep for the purpose of comparing pulmonary host defense mechanisms in the two species. Specific variables studied included (1) characterization of the cell types present in the lung, (2) alveolar macrophage phagocytic and bactericidal functions, (3) measurement of protein levels in lavage fluid, and (4) measurement of Cortisol levels in lavage fluid. While phagocytic cell populations were similar between bighorn and domestic sheep, a significantly higher percentage of lymphocytes were present in bighorns than domestics (20% in bighorn versus 6% in domestic sheep). Significant differences were not observed in the phagocytic or bactericidal tunctions of macrophages between the two species. Significant differences were not observed in either lavage fluid protein levels or in Cortisol levels. |
| doi_str_mv | 10.7589/0090-3558-25.4.514 |
| format | Article |
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Denny ; Leid, R. Wes</creator><creatorcontrib>Silflow, Ronald M ; Foreyt, William J ; Taylor, Stephen M ; Laegreid, William W ; Liggitt, H. Denny ; Leid, R. Wes</creatorcontrib><description>Alveolar macrophages were obtained from Rocky Mountain bighorn sheep (Ovis canadensis canadensis) and domestic sheep for the purpose of comparing pulmonary host defense mechanisms in the two species. Specific variables studied included (1) characterization of the cell types present in the lung, (2) alveolar macrophage phagocytic and bactericidal functions, (3) measurement of protein levels in lavage fluid, and (4) measurement of Cortisol levels in lavage fluid. While phagocytic cell populations were similar between bighorn and domestic sheep, a significantly higher percentage of lymphocytes were present in bighorns than domestics (20% in bighorn versus 6% in domestic sheep). Significant differences were not observed in the phagocytic or bactericidal tunctions of macrophages between the two species. Significant differences were not observed in either lavage fluid protein levels or in Cortisol levels.</description><identifier>ISSN: 0090-3558</identifier><identifier>EISSN: 1943-3700</identifier><identifier>DOI: 10.7589/0090-3558-25.4.514</identifier><identifier>PMID: 2810551</identifier><language>eng</language><publisher>United States: Wildlife Disease Association</publisher><subject>alveolar macrophages ; Animals ; Artiodactyla ; bactericidal ; Bighorn sheep ; Bronchoalveolar Lavage Fluid - analysis ; Bronchoalveolar Lavage Fluid - cytology ; Cell Count - veterinary ; Cortisol ; DISEASE RESISTANCE ; domestic sheep ; experimental study ; FAGOCITOS ; Female ; GLUCOCORTICOIDE ; GLUCOCORTICOIDES ; GLUCOCORTICOIDS ; Hydrocortisone - analysis ; lavage ; Lung - cytology ; Lung - immunology ; Lymphocytes ; Macrophages - immunology ; Male ; NEUMONIA ; OVIN ; OVINOS ; Ovis canadensis canadensis ; PHAGOCYTE ; PHAGOCYTES ; PHAGOCYTOSIS ; PNEUMONIA ; Pneumonia - immunology ; Pneumonia - veterinary ; pneumonia complex ; PNEUMONIE ; Proteins - analysis ; RESISTANCE AUX MALADIES ; RESISTENCIA A LA ENFERMEDAD ; SHEEP ; Sheep Diseases - immunology ; SUSCEPTIBILITY</subject><ispartof>Journal of wildlife diseases, 1989-10, Vol.25 (4), p.514-520</ispartof><rights>Wildlife Disease Association 1989</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b419t-fa70e21438cbc8b0e6de9740be5812f4b11f31e9fe1218a7ba5530c76ca98f503</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://bioone.org/doi/pdf/10.7589/0090-3558-25.4.514$$EPDF$$P50$$Gbioone$$H</linktopdf><link.rule.ids>109,314,780,784,27924,27925,52719</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2810551$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Silflow, Ronald M</creatorcontrib><creatorcontrib>Foreyt, William J</creatorcontrib><creatorcontrib>Taylor, Stephen M</creatorcontrib><creatorcontrib>Laegreid, William W</creatorcontrib><creatorcontrib>Liggitt, H. Denny</creatorcontrib><creatorcontrib>Leid, R. Wes</creatorcontrib><title>COMPARISON OF PULMONARY DEFENSE MECHANISMS IN ROCKY MOUNTAIN BIGHORN (OVIS CANADENSIS CANADENSIS) AND DOMESTIC SHEEP</title><title>Journal of wildlife diseases</title><addtitle>J Wildl Dis</addtitle><description>Alveolar macrophages were obtained from Rocky Mountain bighorn sheep (Ovis canadensis canadensis) and domestic sheep for the purpose of comparing pulmonary host defense mechanisms in the two species. Specific variables studied included (1) characterization of the cell types present in the lung, (2) alveolar macrophage phagocytic and bactericidal functions, (3) measurement of protein levels in lavage fluid, and (4) measurement of Cortisol levels in lavage fluid. While phagocytic cell populations were similar between bighorn and domestic sheep, a significantly higher percentage of lymphocytes were present in bighorns than domestics (20% in bighorn versus 6% in domestic sheep). Significant differences were not observed in the phagocytic or bactericidal tunctions of macrophages between the two species. Significant differences were not observed in either lavage fluid protein levels or in Cortisol levels.</description><subject>alveolar macrophages</subject><subject>Animals</subject><subject>Artiodactyla</subject><subject>bactericidal</subject><subject>Bighorn sheep</subject><subject>Bronchoalveolar Lavage Fluid - analysis</subject><subject>Bronchoalveolar Lavage Fluid - cytology</subject><subject>Cell Count - veterinary</subject><subject>Cortisol</subject><subject>DISEASE RESISTANCE</subject><subject>domestic sheep</subject><subject>experimental study</subject><subject>FAGOCITOS</subject><subject>Female</subject><subject>GLUCOCORTICOIDE</subject><subject>GLUCOCORTICOIDES</subject><subject>GLUCOCORTICOIDS</subject><subject>Hydrocortisone - analysis</subject><subject>lavage</subject><subject>Lung - cytology</subject><subject>Lung - immunology</subject><subject>Lymphocytes</subject><subject>Macrophages - immunology</subject><subject>Male</subject><subject>NEUMONIA</subject><subject>OVIN</subject><subject>OVINOS</subject><subject>Ovis canadensis canadensis</subject><subject>PHAGOCYTE</subject><subject>PHAGOCYTES</subject><subject>PHAGOCYTOSIS</subject><subject>PNEUMONIA</subject><subject>Pneumonia - immunology</subject><subject>Pneumonia - veterinary</subject><subject>pneumonia complex</subject><subject>PNEUMONIE</subject><subject>Proteins - analysis</subject><subject>RESISTANCE AUX MALADIES</subject><subject>RESISTENCIA A LA ENFERMEDAD</subject><subject>SHEEP</subject><subject>Sheep Diseases - immunology</subject><subject>SUSCEPTIBILITY</subject><issn>0090-3558</issn><issn>1943-3700</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkVFv0zAUhS0EGmXwByYh-QUEDynXjr3YjyFN14gmrpoWaU-WkzlbULqMuFXFv8dVqgme4Mm-Ot85uroHoSsC04gL-QVAQhByLgLKp2zKCXuBJkSyMAgjgJdo8gy8Rm-c-wFAuR8u0AUVBDgnE7RPVL6K11mpCqzmeLVd5qqI17d4ls7TokxxniaLuMjKvMRZgdcq-XaLc7UtNrEfv2Y3C7Uu8Cf1PStxEhfxzJv--n7GcTHDM5Wn5SZLcLlI09Vb9KoxnbPvzu8l2s7TTbIIluomS-JlUDEi90FjIrCUsFDUVS0qsNd3VkYMKssFoQ2rCGlCYmVjCSXCRJXhPIQ6uq6NFA2H8BJ9HHOfhv7nwbq93rWutl1nHm1_cDqSVEpO-D9BwhnIUDAP0hGsh965wTb6aWh3ZvilCehTJ_p0cn06uaZcM-078ab35_RDtbN3z5ZzCV7_MOoP7f3DsR2sdjvTdZ6m-ng8_pFzNXKN6bW5H1qnt6UEvz8VXoRRrNq-f7T_s9dvn0OgRA</recordid><startdate>19891001</startdate><enddate>19891001</enddate><creator>Silflow, Ronald M</creator><creator>Foreyt, William J</creator><creator>Taylor, Stephen M</creator><creator>Laegreid, William W</creator><creator>Liggitt, H. Denny</creator><creator>Leid, R. Wes</creator><general>Wildlife Disease Association</general><general>Wildlife Dis Assoc</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7T5</scope><scope>C1K</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>19891001</creationdate><title>COMPARISON OF PULMONARY DEFENSE MECHANISMS IN ROCKY MOUNTAIN BIGHORN (OVIS CANADENSIS CANADENSIS) AND DOMESTIC SHEEP</title><author>Silflow, Ronald M ; Foreyt, William J ; Taylor, Stephen M ; Laegreid, William W ; Liggitt, H. Denny ; Leid, R. Wes</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b419t-fa70e21438cbc8b0e6de9740be5812f4b11f31e9fe1218a7ba5530c76ca98f503</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>alveolar macrophages</topic><topic>Animals</topic><topic>Artiodactyla</topic><topic>bactericidal</topic><topic>Bighorn sheep</topic><topic>Bronchoalveolar Lavage Fluid - analysis</topic><topic>Bronchoalveolar Lavage Fluid - cytology</topic><topic>Cell Count - veterinary</topic><topic>Cortisol</topic><topic>DISEASE RESISTANCE</topic><topic>domestic sheep</topic><topic>experimental study</topic><topic>FAGOCITOS</topic><topic>Female</topic><topic>GLUCOCORTICOIDE</topic><topic>GLUCOCORTICOIDES</topic><topic>GLUCOCORTICOIDS</topic><topic>Hydrocortisone - analysis</topic><topic>lavage</topic><topic>Lung - cytology</topic><topic>Lung - immunology</topic><topic>Lymphocytes</topic><topic>Macrophages - immunology</topic><topic>Male</topic><topic>NEUMONIA</topic><topic>OVIN</topic><topic>OVINOS</topic><topic>Ovis canadensis canadensis</topic><topic>PHAGOCYTE</topic><topic>PHAGOCYTES</topic><topic>PHAGOCYTOSIS</topic><topic>PNEUMONIA</topic><topic>Pneumonia - immunology</topic><topic>Pneumonia - veterinary</topic><topic>pneumonia complex</topic><topic>PNEUMONIE</topic><topic>Proteins - analysis</topic><topic>RESISTANCE AUX MALADIES</topic><topic>RESISTENCIA A LA ENFERMEDAD</topic><topic>SHEEP</topic><topic>Sheep Diseases - immunology</topic><topic>SUSCEPTIBILITY</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Silflow, Ronald M</creatorcontrib><creatorcontrib>Foreyt, William J</creatorcontrib><creatorcontrib>Taylor, Stephen M</creatorcontrib><creatorcontrib>Laegreid, William W</creatorcontrib><creatorcontrib>Liggitt, H. Denny</creatorcontrib><creatorcontrib>Leid, R. Wes</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Immunology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of wildlife diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Silflow, Ronald M</au><au>Foreyt, William J</au><au>Taylor, Stephen M</au><au>Laegreid, William W</au><au>Liggitt, H. Denny</au><au>Leid, R. Wes</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>COMPARISON OF PULMONARY DEFENSE MECHANISMS IN ROCKY MOUNTAIN BIGHORN (OVIS CANADENSIS CANADENSIS) AND DOMESTIC SHEEP</atitle><jtitle>Journal of wildlife diseases</jtitle><addtitle>J Wildl Dis</addtitle><date>1989-10-01</date><risdate>1989</risdate><volume>25</volume><issue>4</issue><spage>514</spage><epage>520</epage><pages>514-520</pages><issn>0090-3558</issn><eissn>1943-3700</eissn><abstract>Alveolar macrophages were obtained from Rocky Mountain bighorn sheep (Ovis canadensis canadensis) and domestic sheep for the purpose of comparing pulmonary host defense mechanisms in the two species. Specific variables studied included (1) characterization of the cell types present in the lung, (2) alveolar macrophage phagocytic and bactericidal functions, (3) measurement of protein levels in lavage fluid, and (4) measurement of Cortisol levels in lavage fluid. While phagocytic cell populations were similar between bighorn and domestic sheep, a significantly higher percentage of lymphocytes were present in bighorns than domestics (20% in bighorn versus 6% in domestic sheep). Significant differences were not observed in the phagocytic or bactericidal tunctions of macrophages between the two species. Significant differences were not observed in either lavage fluid protein levels or in Cortisol levels.</abstract><cop>United States</cop><pub>Wildlife Disease Association</pub><pmid>2810551</pmid><doi>10.7589/0090-3558-25.4.514</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0090-3558 |
| ispartof | Journal of wildlife diseases, 1989-10, Vol.25 (4), p.514-520 |
| issn | 0090-3558 1943-3700 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_79299515 |
| source | MEDLINE; BioOne Open Access Titles; Allen Press Journals; EZB-FREE-00999 freely available EZB journals |
| subjects | alveolar macrophages Animals Artiodactyla bactericidal Bighorn sheep Bronchoalveolar Lavage Fluid - analysis Bronchoalveolar Lavage Fluid - cytology Cell Count - veterinary Cortisol DISEASE RESISTANCE domestic sheep experimental study FAGOCITOS Female GLUCOCORTICOIDE GLUCOCORTICOIDES GLUCOCORTICOIDS Hydrocortisone - analysis lavage Lung - cytology Lung - immunology Lymphocytes Macrophages - immunology Male NEUMONIA OVIN OVINOS Ovis canadensis canadensis PHAGOCYTE PHAGOCYTES PHAGOCYTOSIS PNEUMONIA Pneumonia - immunology Pneumonia - veterinary pneumonia complex PNEUMONIE Proteins - analysis RESISTANCE AUX MALADIES RESISTENCIA A LA ENFERMEDAD SHEEP Sheep Diseases - immunology SUSCEPTIBILITY |
| title | COMPARISON OF PULMONARY DEFENSE MECHANISMS IN ROCKY MOUNTAIN BIGHORN (OVIS CANADENSIS CANADENSIS) AND DOMESTIC SHEEP |
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