Production of monoclonal antibodies against interleukin-1α and -1β: Development of two enzyme immunometric assays (EIA) using acetylcholinesterase and their application to biological media

We describe two series of monoclonal antibodies (mAbs) directed against human interleukin-1α (36 mAbs) and -1β (11 mAbs). The binding compatibility of each of mAb was studied using biotin-labelled mAbs in immunometric tests. Among the different pairs of compatible mAbs, we selected one pair for each...

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Veröffentlicht in:Journal of immunological methods 1989-10, Vol.123 (2), p.193-210
Hauptverfasser: Grassi, Jacques, Frobert, Yveline, Pradelles, Philippe, Chercuitte, Francine, Gruaz, Dominique, Dayer, Jean-Michel, Poubelle, Patrice E.
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Sprache:eng
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