v-src genes stimulate neurite outgrowth in pheochromocytoma (PC12) variants unresponsive to neurotrophic factors

The NGF‐nonresponsive rat pheochromocytoma PC12 variant nnr5, isolated by Green et al. (J Cell Biol 102:830–843, 1986), responds poorly or not at all to fibroblast growth factor. Transformation of PC‐12nnr5 cells with v–src‐expressing retroviruses results in vigorous neurite outgrowth, similar to th...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of neuroscience research 1989-09, Vol.24 (1), p.67-71
Hauptverfasser:	Eveleth, D. D., Hanecak, R., Fox, G. M., Fan, H., Bradshaw, R. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Axons - physiology Cloning, Molecular Nerve Growth Factors - physiology neurotrophic factors Oncogenes - physiology PC12 Pheochromocytoma Rats Retroviridae - genetics Tumor Cells, Cultured - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!