The role of non-esterified fatty acids in the deterioration of glucose tolerance in Caucasian subjects : results of the Paris Prospective Study

Although an increased plasma non-esterified fatty acid (NEFA) concentration has been shown to increase insulin resistance (Randle cycle), decrease insulin secretion and increase hepatic gluconeogenesis, the effect of NEFA on the deterioration of glucose tolerance has not been studied prospectively i...

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