Inhibition of Melanoma Cell Binding to Type IV Collagen by Analogs of Cell Adhesion Regulator

Integrin-mediated tumor cell adhesion to type IV collagen is believed to play a role in the invasion of basement membrane proteins and the subsequent metastatic process. The cellular protein CAR (cell adhesion regulator) has been proposed to influence integrin-mediated binding to extracellular matri...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of medicinal chemistry 1997-09, Vol.40 (19), p.3077-3084
Hauptverfasser:	Lauer, Janelle L, Furcht, Leo T, Fields, Gregg B
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Antineoplastic agents ATPases Associated with Diverse Cellular Activities Basement Membrane Biological and medical sciences Cell Adhesion - drug effects Cell Adhesion - physiology Cell Adhesion Molecules - chemistry Cell Membrane Permeability Collagen General aspects Humans Kinetics Medical sciences Melanoma Metalloendopeptidases Neoplasm Metastasis Oligopeptides - chemical synthesis Oligopeptides - chemistry Oligopeptides - pharmacology Peptide Fragments - chemical synthesis Peptide Fragments - chemistry Peptide Fragments - pharmacology Pharmacology. Drug treatments Structure-Activity Relationship Tumor Cells, Cultured
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!