Glucose-induced microautophagy in Pichia pastoris requires the alpha-subunit of phosphofructokinase

We have characterized biochemically, morphologically, and genetically two distinct pathways for the selective degradation of peroxisomes in Pichia pastoris. These pathways are independently regulated and analogous to microautophagy and macroautophagy that have been defined in mammalian cells. When P...

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Veröffentlicht in:	Journal of cell science 1997-08, Vol.110 (16), p.1935-1945
Hauptverfasser:	Yuan, W, Tuttle, D.L, Shi, Y.J, Ralph, G.S, Dunn, W.A. Jr
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Autophagy - drug effects Autophagy - physiology Base Sequence Cytosol - enzymology genbank/u73376 genes Genes, Fungal Glucose - pharmacology Humans Macromolecular Substances Mammals Methanol - metabolism Microbodies - enzymology Molecular Sequence Data Mutation nucleotide sequences peroxisomes pfk1 gene Phosphofructokinase-1 - biosynthesis Phosphofructokinase-1 - chemistry Phosphofructokinase-1 - metabolism Pichia - drug effects Pichia - genetics Pichia - physiology RNA, Messenger - metabolism Saccharomyces cerevisiae - enzymology Sequence Alignment Sequence Homology, Amino Acid Transformation, Genetic
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