Phase shift of the hepatic vein flow velocity waveform in chronic liver disease: Experimental and clinical studies

We examined animal models and studied patients with chronic liver disease to evaluate phase shift of the flow-velocity waveform of the hepatic vein (HV). We decided the Doppler-Pressure (DP) ratio using electrocardiography, the HV Doppler waveform and HV pressure curves, and we calculated the DP rat...

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Veröffentlicht in:Ultrasound in medicine & biology 1997, Vol.23 (6), p.821-828
Hauptverfasser: Hamato, Noriyuki, Moriyasu, Fuminori, Someda, Hitoshi, Nishikawa, Koji, Chiba, Tsutomu, Okuma, Minoru
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container_end_page 828
container_issue 6
container_start_page 821
container_title Ultrasound in medicine & biology
container_volume 23
creator Hamato, Noriyuki
Moriyasu, Fuminori
Someda, Hitoshi
Nishikawa, Koji
Chiba, Tsutomu
Okuma, Minoru
description We examined animal models and studied patients with chronic liver disease to evaluate phase shift of the flow-velocity waveform of the hepatic vein (HV). We decided the Doppler-Pressure (DP) ratio using electrocardiography, the HV Doppler waveform and HV pressure curves, and we calculated the DP ratios. In animal models, the mean DP ratio was 1.04 in controls, 0.68 in cirrhosis, and 1.22 in fatty liver. There were significant differences among these groups ( p < 0.005). In the clinical study, the mean DP ratio was 1.03 in controls, 0.95 in chronic hepatitis and 0.79 in cirrhosis. The DP ratio in the Cirrhosis Group was significantly different from that in the Control Group ( p < 0.001) and that in the Chronic Hepatitis Group ( p < 0.05). We conclude that the DP ratio is decreased in certain hepatic disease states.
doi_str_mv 10.1016/S0301-5629(97)00048-3
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Abdomen</topic><topic>Disease Models, Animal</topic><topic>Doppler</topic><topic>Female</topic><topic>Hepatic vein</topic><topic>Hepatic Veins - diagnostic imaging</topic><topic>Hepatic Veins - physiopathology</topic><topic>Humans</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Liver - blood supply</topic><topic>Liver Diseases - diagnostic imaging</topic><topic>Liver Diseases - physiopathology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Rabbits</topic><topic>Ultrasonic investigative techniques</topic><topic>Ultrasonography, Doppler - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hamato, Noriyuki</creatorcontrib><creatorcontrib>Moriyasu, Fuminori</creatorcontrib><creatorcontrib>Someda, Hitoshi</creatorcontrib><creatorcontrib>Nishikawa, Koji</creatorcontrib><creatorcontrib>Chiba, Tsutomu</creatorcontrib><creatorcontrib>Okuma, Minoru</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Ultrasound in medicine &amp; biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hamato, Noriyuki</au><au>Moriyasu, Fuminori</au><au>Someda, Hitoshi</au><au>Nishikawa, Koji</au><au>Chiba, Tsutomu</au><au>Okuma, Minoru</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Phase shift of the hepatic vein flow velocity waveform in chronic liver disease: Experimental and clinical studies</atitle><jtitle>Ultrasound in medicine &amp; biology</jtitle><addtitle>Ultrasound Med Biol</addtitle><date>1997</date><risdate>1997</risdate><volume>23</volume><issue>6</issue><spage>821</spage><epage>828</epage><pages>821-828</pages><issn>0301-5629</issn><eissn>1879-291X</eissn><coden>USMBA3</coden><abstract>We examined animal models and studied patients with chronic liver disease to evaluate phase shift of the flow-velocity waveform of the hepatic vein (HV). We decided the Doppler-Pressure (DP) ratio using electrocardiography, the HV Doppler waveform and HV pressure curves, and we calculated the DP ratios. In animal models, the mean DP ratio was 1.04 in controls, 0.68 in cirrhosis, and 1.22 in fatty liver. There were significant differences among these groups ( p &lt; 0.005). In the clinical study, the mean DP ratio was 1.03 in controls, 0.95 in chronic hepatitis and 0.79 in cirrhosis. The DP ratio in the Cirrhosis Group was significantly different from that in the Control Group ( p &lt; 0.001) and that in the Chronic Hepatitis Group ( p &lt; 0.05). We conclude that the DP ratio is decreased in certain hepatic disease states.</abstract><cop>Amsterdam</cop><pub>Elsevier Inc</pub><pmid>9300985</pmid><doi>10.1016/S0301-5629(97)00048-3</doi><tpages>8</tpages></addata></record>
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source Elsevier ScienceDirect Journals Complete - AutoHoldings; MEDLINE
subjects Adult
Aged
Animals
Biological and medical sciences
Blood Flow Velocity - physiology
Cardiovascular system
Chronic Disease
Chronic liver disease
Digestive system. Abdomen
Disease Models, Animal
Doppler
Female
Hepatic vein
Hepatic Veins - diagnostic imaging
Hepatic Veins - physiopathology
Humans
Investigative techniques, diagnostic techniques (general aspects)
Liver - blood supply
Liver Diseases - diagnostic imaging
Liver Diseases - physiopathology
Male
Medical sciences
Middle Aged
Rabbits
Ultrasonic investigative techniques
Ultrasonography, Doppler - methods
title Phase shift of the hepatic vein flow velocity waveform in chronic liver disease: Experimental and clinical studies
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