A morphological study of histological activity index (HAI) and scoring system in hepatitis-C
A retrospective morphological study of 25 cases of serologically positive chronic hepatitis C was carried out. Paraffin embedded sections were stained with haematoxylin, eosin and Gomori reticulin stains. The histological features were scored according to both Knodell and Scheuer systems. The result...
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| Veröffentlicht in: | Journal of the Pakistan Medical Association 1997-06, Vol.47 (6), p.162-165 |
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| container_title | Journal of the Pakistan Medical Association |
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| creator | Mushtaq, S Muzaffar, M Khadim, M T Tariq, W Z Mamoon, N |
| description | A retrospective morphological study of 25 cases of serologically positive chronic hepatitis C was carried out. Paraffin embedded sections were stained with haematoxylin, eosin and Gomori reticulin stains. The histological features were scored according to both Knodell and Scheuer systems. The results of Knodell showed 32% cases scored between 4-8 and 48% between 9-12. Cases of conventional category of chronic persistent hepatitis scored between 1-3 and chronic active hepatitis score ranged between 4-12. The scoring systems provide a good guideline for management/selection of cases for interferone therapy and subsequent evaluation and assessment of the cases. |
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Paraffin embedded sections were stained with haematoxylin, eosin and Gomori reticulin stains. The histological features were scored according to both Knodell and Scheuer systems. The results of Knodell showed 32% cases scored between 4-8 and 48% between 9-12. Cases of conventional category of chronic persistent hepatitis scored between 1-3 and chronic active hepatitis score ranged between 4-12. 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Paraffin embedded sections were stained with haematoxylin, eosin and Gomori reticulin stains. The histological features were scored according to both Knodell and Scheuer systems. The results of Knodell showed 32% cases scored between 4-8 and 48% between 9-12. Cases of conventional category of chronic persistent hepatitis scored between 1-3 and chronic active hepatitis score ranged between 4-12. The scoring systems provide a good guideline for management/selection of cases for interferone therapy and subsequent evaluation and assessment of the cases.</description><subject>Adult</subject><subject>Analysis of Variance</subject><subject>Chronic Disease</subject><subject>Female</subject><subject>Fibrosis - diagnosis</subject><subject>Hepatitis C - pathology</subject><subject>Humans</subject><subject>Male</subject><subject>Retrospective Studies</subject><subject>Severity of Illness Index</subject><issn>0030-9982</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kEtLxDAYRbNQxnH0JwhZiS4KXx59ZFmKOgMDbmYplDSPaaRtapOK_fcqFlcXzj3cxb1AWwAGiRAFvULXIbwD0CwF2KCNYEBIJrborcS9n8bWd_7slOxwiLNesLe4dSH-U6mi-3RxwW7Q5gs_7MvDI5aDxkH5yQ1nHJYQTf9T49aMMrroQlLdoEsru2Bu19yh0_PTqdonx9eXQ1Uek5FQEhPCbdGIRnFpCQDhRGjKVS5ypjJluc1IwW2uGiEMoyZnNAML2hKiRQ6WsR26_5sdJ_8xmxDr3gVluk4Oxs-hzgUt0pT9inerODe90fU4uV5OS72-wb4BPplaYA</recordid><startdate>199706</startdate><enddate>199706</enddate><creator>Mushtaq, S</creator><creator>Muzaffar, M</creator><creator>Khadim, M T</creator><creator>Tariq, W Z</creator><creator>Mamoon, N</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>199706</creationdate><title>A morphological study of histological activity index (HAI) and scoring system in hepatitis-C</title><author>Mushtaq, S ; Muzaffar, M ; Khadim, M T ; Tariq, W Z ; Mamoon, N</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p121t-14f8b9bc4af1001419d24c7973c6cf4f6184f7cb99e32e73260f0df11d970f33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Adult</topic><topic>Analysis of Variance</topic><topic>Chronic Disease</topic><topic>Female</topic><topic>Fibrosis - diagnosis</topic><topic>Hepatitis C - pathology</topic><topic>Humans</topic><topic>Male</topic><topic>Retrospective Studies</topic><topic>Severity of Illness Index</topic><toplevel>online_resources</toplevel><creatorcontrib>Mushtaq, S</creatorcontrib><creatorcontrib>Muzaffar, M</creatorcontrib><creatorcontrib>Khadim, M T</creatorcontrib><creatorcontrib>Tariq, W Z</creatorcontrib><creatorcontrib>Mamoon, N</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the Pakistan Medical Association</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mushtaq, S</au><au>Muzaffar, M</au><au>Khadim, M T</au><au>Tariq, W Z</au><au>Mamoon, N</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A morphological study of histological activity index (HAI) and scoring system in hepatitis-C</atitle><jtitle>Journal of the Pakistan Medical Association</jtitle><addtitle>J Pak Med Assoc</addtitle><date>1997-06</date><risdate>1997</risdate><volume>47</volume><issue>6</issue><spage>162</spage><epage>165</epage><pages>162-165</pages><issn>0030-9982</issn><abstract>A retrospective morphological study of 25 cases of serologically positive chronic hepatitis C was carried out. Paraffin embedded sections were stained with haematoxylin, eosin and Gomori reticulin stains. The histological features were scored according to both Knodell and Scheuer systems. The results of Knodell showed 32% cases scored between 4-8 and 48% between 9-12. Cases of conventional category of chronic persistent hepatitis scored between 1-3 and chronic active hepatitis score ranged between 4-12. The scoring systems provide a good guideline for management/selection of cases for interferone therapy and subsequent evaluation and assessment of the cases.</abstract><cop>Pakistan</cop><pmid>9301169</pmid><tpages>4</tpages></addata></record> |
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| ispartof | Journal of the Pakistan Medical Association, 1997-06, Vol.47 (6), p.162-165 |
| issn | 0030-9982 |
| language | eng |
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| source | MEDLINE; EZB Electronic Journals Library |
| subjects | Adult Analysis of Variance Chronic Disease Female Fibrosis - diagnosis Hepatitis C - pathology Humans Male Retrospective Studies Severity of Illness Index |
| title | A morphological study of histological activity index (HAI) and scoring system in hepatitis-C |
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