Radioactive Metal Complexes with Affinity for Tumors. II. Biodistribution of Radioactivity in Cellular and Subcellular Fractions of Tumor Tissues

The 99mTc and 57Co complexes of ethylenediamine-N, N-diacetic acid (EDDA) are accumulated in tumor tissue. The complexes and related radioactive compounds were administered to experimental animals bearing Ehrlich tumor, and the blood, tumor, abscess, and other tissues were separated, fractionated an...

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Veröffentlicht in:	Chemical & pharmaceutical bulletin 1989/07/25, Vol.37(7), pp.1874-1876
Hauptverfasser:	KARUBE, Yoshiharu, IWAMOTO, Koji, MIURA, Junko, TAKATA, Jiro, MATSUSHIMA, Yoshikazu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic agents Biological and medical sciences Chemotherapy Co Cobalt Radioisotopes Edetic Acid Ehrlich tumor ethylenediamine-N, N-diacetic acid In Vitro Techniques Medical sciences metal complex Mice Neoplasms, Experimental - diagnostic imaging Organotechnetium Compounds Pharmacology. Drug treatments radioactivity Radionuclide Imaging Subcellular Fractions - metabolism Tc Tissue Distribution tumor scintigraphy
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