Negative Inotropic Effect of Methylecgonidine, a Major Product of Cocaine Base Pyrolysis, on Ferret and Human Myocardium

This study examined the physiological effects and potential mechanisms of action of methylecgonidine (MEG), the major pyrolysis product from smoking "crack cocaine," on cardiac function. Ferret right ventricular papillary muscles and human ventricular trabeculae were isolated and placed in...

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