Evaluation of 99Tcm-bicisate as a renal imaging agent

Tc-bicisate (Tc-ECD), often used as a brain perfusion agent, is rapidly converted following intravenous injection to the polar monoacid (Tc-ECM) and diacid (Tc-EC) metabolites. Such polar metabolites, which are eliminated principally by renal clearance, are potential renal imaging agents. In this st...

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Veröffentlicht in:	Nuclear medicine communications 1997-08, Vol.18 (8), p.771-775
Hauptverfasser:	OZKER, K, KABASAKAL, L, LIU, Y, HELLMAN, R S, ISITMAN, A, KRASNOW, A Z, COLLIER, B D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Biotransformation Contrast media. Radiopharmaceuticals Cysteine - analogs & derivatives Cysteine - pharmacokinetics Humans Investigative techniques, diagnostic techniques (general aspects) Iodine Radioisotopes - pharmacokinetics Iodohippuric Acid - pharmacokinetics Kidney - diagnostic imaging Kidney - metabolism Medical sciences Metabolic Clearance Rate Organotechnetium Compounds - pharmacokinetics Pharmacology. Drug treatments Rabbits Radionuclide Imaging Radionuclide investigations Radiopharmaceuticals - pharmacokinetics Technetium Tc 99m Mertiatide - pharmacokinetics Urinary system
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