Immunoreactive T and Tn epitopes in cancer diagnosis, prognosis, and immunotherapy

Aberrant glycosylation is a hallmark of cancer cells. The blood group precursors T (Thomsen-Friedenreich) and Tn epitopes are shielded in healthy and benign-diseased tissues but uncovered in approx. 90% of carcinomas. T and Tn glycoproteins are specific, autoimmunogenic pancarcinoma antigens. These...

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Veröffentlicht in:	Journal of molecular medicine (Berlin, Germany) Germany), 1997-08, Vol.75 (8), p.594-602
1. Verfasser:	SPRINGER, G. F
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, Tumor-Associated, Carbohydrate - chemistry Antigens, Tumor-Associated, Carbohydrate - metabolism Antigens, Tumor-Associated, Carbohydrate - physiology Biological and medical sciences Epitopes - physiology Humans Medical sciences Multiple tumors. Solid tumors. Tumors in childhood (general aspects) Neoplasm Invasiveness - immunology Neoplasm Metastasis - immunology Neoplasms - diagnosis Neoplasms - immunology Neoplasms - pathology Neoplasms - therapy Prognosis Tumors
Online-Zugang:	Volltext
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