Tumour necrosis factor-α induces cyclo-oxygenase-2 gene expression in first trimester trophoblasts: suppression by glucocorticoids and NSAIDs

Tumour necrosis factor-α (TNF-α) is a pleiotropic cytokine which stimulates the synthesis and release of prostaglandins (PGs) in several in vitro and in vivo models of preterm labour. While TNF-α-stimulated PG production has been described in decidual, amnion and myometrial cells, to date no studies...

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