MAZ, a Myc-associated zinc finger protein, is essential for the ME1a1-mediated expression of the c-myc gene during neuroectodermal differentiation of P19 cells

To investigate whether MAZ (Myc-associated zinc finger protein) affects the expression of the c-myc gene during the retinoic acid-induced (RA-induced) neuroectodermal differentiation of P19 embryonal carcinoma (EC) cells, we introduced a CAT reporter construct, human c-myc promoter/CAT (pMyc2CAT), a...

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Veröffentlicht in:	Oncogene 1997-09, Vol.15 (10), p.1123-1131
Hauptverfasser:	KOMATSU, M, LI, H.-O, TSUTSUI, H, ITAKURA, K, MATSUMURA, M, YOKOYAMA, K. K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences c-Myc protein CAT gene Cell Differentiation Cell Nucleus - metabolism Cell physiology Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes Deoxyribonucleic acid DNA DNA - metabolism DNA-Binding Proteins - metabolism Electrophoretic mobility Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Developmental - drug effects Genes, myc Mice Molecular and cellular biology Myc protein Neurons - cytology Promoter Regions, Genetic Retinoic acid RNA, Messenger - genetics Transcription Factors - physiology Transcription, Genetic Transformed cells Tretinoin - pharmacology Zinc finger proteins Zinc Fingers
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