Sodium dodecylsulphate induces a breach in the blood-brain barrier and enables a West Nile virus variant to penetrate into mouse brain

A novel and convenient assay was used to determine the effect of recombinant Interleukin-2 (IL-2) on the function of the blood-brain barrier (BBB). The assay is based on a variant of the West Nile virus, WN-25, which had lost its neuroinvasiveness but not its neurovirulance. WN-25, when injected int...

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Veröffentlicht in:	Brain research 1989-09, Vol.496 (1), p.314-316
Hauptverfasser:	Kobiler, David, Lustig, Shlomo, Gozes, Yehoshua, Ben-Nathan, David, Akov, Yair
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blood-brain barrier Blood-Brain Barrier - drug effects General pharmacology Interleukin-2 - pharmacology Medical sciences Mice Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions Pharmacology. Drug treatments Sodium Dodecyl Sulfate - pharmacology Sodium dodecylsulphate West Nile Fever West Nile virus - pathogenicity West Nile virus variant
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