Pharmacokinetics and systemic bioavailability of menogaril, and anthracycline antitumor agent, in the mouse, dog, and monkey

Menogaril is an antitumor agent of the anthracycline type which is less cardiotoxic than doxorubicin in a chronic rabbit model and is active in experimental tumor systems when given by p.o. or parenteral routes. It is currently undergoing i.v. and p.o. Phase II clinical evaluation. We report here th...

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