Effect of Interferon-α on the Expression and Release of the CD23 Molecule in Hairy Cell Leukemia

Hairy cells are stimulated to DNA synthesis by low molecular weight B cell growth factor (LMW-BCGF) and this proliferative response is suppressed by interferon (IFN)-α, both in vitro and in vivo. The suggestion that the CD23 molecule (FcϵII receptor) might be involved in the signalling pathway of LM...

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Veröffentlicht in:	Blood 1989-11, Vol.74 (7), p.2455-2463
Hauptverfasser:	Génot, Elisabeth, Sarfati, Marie, Sigaux, François, Petit-Koskas, Elisabeth, Billard, Christian, Mathiot, Claire, Falcoff, Ernesto, Delespesse, Guy, Kolb, Jean-Pierre
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, Differentiation, B-Lymphocyte - metabolism Antigens, Differentiation, B-Lymphocyte - physiology Antineoplastic agents B-Lymphocytes - immunology Biological and medical sciences Chemotherapy Flow Cytometry Humans Immunologic Techniques Immunotherapy In Vitro Techniques Interferon Type I - pharmacology Interferon Type I - therapeutic use Interleukin-4 - pharmacology Leukemia, Hairy Cell - immunology Lymphocyte Activation Medical sciences Pharmacology. Drug treatments Receptors, Fc - metabolism Receptors, Fc - physiology Receptors, IgE Recombinant Proteins Solubility
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