Elective versus therapeutic neck dissection in early carcinoma of the oral tongue
A prospective, randomized trial was carried out to assess the value of elective versus therapeutic neck dissection in early squamous cell carcinoma of the oral tongue. Disease-free survival (median follow-up 20 months) was 52 percent versus 63 percent in patients who underwent hemiglossectomy alone...
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| Veröffentlicht in: | The American journal of surgery 1989-10, Vol.158 (4), p.309-313 |
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| creator | Fakih, Abdul R. Rao, Raja S. Borges, Anita M. Patel, Ashraf R. |
| description | A prospective, randomized trial was carried out to assess the value of elective versus therapeutic neck dissection in early squamous cell carcinoma of the oral tongue. Disease-free survival (median follow-up 20 months) was 52 percent versus 63 percent in patients who underwent hemiglossectomy alone and those who underwent hemiglossectomy and radical neck dissection, respectively (difference not statisti cally significant). Patients with a tumor depth of less than 4 mm did significantly better than those with a tumor depth of greater than 4 mm; they were also more likely to have uninvolved nodes at elective radical neck dissection compared with thost with a tumor depth of greater than 4 mm. However, when the survival rates of patients in the two treatment groups were compared with respect to a tumor depth of 4 mm, there was no significant difference between the hemiglossectomy and the hemiglossectomy and radical neck dissection groups. A policy of interval elective radical neck dissection only in those with a tumor depth of greater than 4 mm may optimize cure rates and avoid neck dissection in those unlikely to develop neck recurrence. |
| doi_str_mv | 10.1016/0002-9610(89)90122-0 |
| format | Article |
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Disease-free survival (median follow-up 20 months) was 52 percent versus 63 percent in patients who underwent hemiglossectomy alone and those who underwent hemiglossectomy and radical neck dissection, respectively (difference not statisti cally significant). Patients with a tumor depth of less than 4 mm did significantly better than those with a tumor depth of greater than 4 mm; they were also more likely to have uninvolved nodes at elective radical neck dissection compared with thost with a tumor depth of greater than 4 mm. However, when the survival rates of patients in the two treatment groups were compared with respect to a tumor depth of 4 mm, there was no significant difference between the hemiglossectomy and the hemiglossectomy and radical neck dissection groups. A policy of interval elective radical neck dissection only in those with a tumor depth of greater than 4 mm may optimize cure rates and avoid neck dissection in those unlikely to develop neck recurrence.</description><identifier>ISSN: 0002-9610</identifier><identifier>EISSN: 1879-1883</identifier><identifier>DOI: 10.1016/0002-9610(89)90122-0</identifier><identifier>PMID: 2802032</identifier><identifier>CODEN: AJSUAB</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; Aged ; Biological and medical sciences ; Carcinoma, Squamous Cell - mortality ; Carcinoma, Squamous Cell - pathology ; Carcinoma, Squamous Cell - surgery ; Evaluation Studies as Topic ; Female ; Glossectomy ; Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics ; Humans ; Male ; Medical sciences ; Middle Aged ; Neck Dissection ; Neoplasm Recurrence, Local ; Neoplasm Staging ; Prospective Studies ; Random Allocation ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Surgery of the upper aerodigestive tract ; Tongue Neoplasms - mortality ; Tongue Neoplasms - pathology ; Tongue Neoplasms - surgery</subject><ispartof>The American journal of surgery, 1989-10, Vol.158 (4), p.309-313</ispartof><rights>1989</rights><rights>1990 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c452t-98eb8ac2998102e1af3d05a81896642082475e7db9f8eb3d53fc41be4897b0423</citedby><cites>FETCH-LOGICAL-c452t-98eb8ac2998102e1af3d05a81896642082475e7db9f8eb3d53fc41be4897b0423</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/0002961089901220$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>309,310,314,776,780,785,786,3537,23909,23910,25118,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=6937536$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2802032$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fakih, Abdul R.</creatorcontrib><creatorcontrib>Rao, Raja S.</creatorcontrib><creatorcontrib>Borges, Anita M.</creatorcontrib><creatorcontrib>Patel, Ashraf R.</creatorcontrib><title>Elective versus therapeutic neck dissection in early carcinoma of the oral tongue</title><title>The American journal of surgery</title><addtitle>Am J Surg</addtitle><description>A prospective, randomized trial was carried out to assess the value of elective versus therapeutic neck dissection in early squamous cell carcinoma of the oral tongue. Disease-free survival (median follow-up 20 months) was 52 percent versus 63 percent in patients who underwent hemiglossectomy alone and those who underwent hemiglossectomy and radical neck dissection, respectively (difference not statisti cally significant). Patients with a tumor depth of less than 4 mm did significantly better than those with a tumor depth of greater than 4 mm; they were also more likely to have uninvolved nodes at elective radical neck dissection compared with thost with a tumor depth of greater than 4 mm. However, when the survival rates of patients in the two treatment groups were compared with respect to a tumor depth of 4 mm, there was no significant difference between the hemiglossectomy and the hemiglossectomy and radical neck dissection groups. A policy of interval elective radical neck dissection only in those with a tumor depth of greater than 4 mm may optimize cure rates and avoid neck dissection in those unlikely to develop neck recurrence.</description><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Carcinoma, Squamous Cell - mortality</subject><subject>Carcinoma, Squamous Cell - pathology</subject><subject>Carcinoma, Squamous Cell - surgery</subject><subject>Evaluation Studies as Topic</subject><subject>Female</subject><subject>Glossectomy</subject><subject>Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Neck Dissection</subject><subject>Neoplasm Recurrence, Local</subject><subject>Neoplasm Staging</subject><subject>Prospective Studies</subject><subject>Random Allocation</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgery of the upper aerodigestive tract</subject><subject>Tongue Neoplasms - mortality</subject><subject>Tongue Neoplasms - pathology</subject><subject>Tongue Neoplasms - surgery</subject><issn>0002-9610</issn><issn>1879-1883</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LxDAQhoMouq7-A4UcRPRQzVfb5CLIsn7Aggh6Dmk61Wi3WZN2Yf-9rVv26FyGYZ53GB6Ezii5oYRmt4QQlqiMkiuprhWhjCVkD02ozFVCpeT7aLJDjtBxjF_9SKngh-iQScIIZxP0Oq_Btm4NeA0hdhG3nxDMCrrWWdyA_cali3FAfINdg8GEeoOtCdY1fmmwr4YE9sHUuPXNRwcn6KAydYTTsU_R-8P8bfaULF4en2f3i8SKlLWJklBIY5lSkhIG1FS8JKmRVKosE4xIJvIU8rJQVU_yMuWVFbQAIVVeEMH4FF1u766C_-kgtnrpooW6Ng34LupcsSznfU2R2II2-BgDVHoV3NKEjaZEDyb1oEkPmrRU-s-kJn3sfLzfFUsod6FRXb-_GPcmWlNXwTTWxR2WKZ6nPOuxuy0GvYu1g6CjddBYKF3oterSu___-AVwvI59</recordid><startdate>19891001</startdate><enddate>19891001</enddate><creator>Fakih, Abdul R.</creator><creator>Rao, Raja S.</creator><creator>Borges, Anita M.</creator><creator>Patel, Ashraf R.</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19891001</creationdate><title>Elective versus therapeutic neck dissection in early carcinoma of the oral tongue</title><author>Fakih, Abdul R. ; Rao, Raja S. ; Borges, Anita M. ; Patel, Ashraf R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c452t-98eb8ac2998102e1af3d05a81896642082475e7db9f8eb3d53fc41be4897b0423</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Carcinoma, Squamous Cell - mortality</topic><topic>Carcinoma, Squamous Cell - pathology</topic><topic>Carcinoma, Squamous Cell - surgery</topic><topic>Evaluation Studies as Topic</topic><topic>Female</topic><topic>Glossectomy</topic><topic>Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Neck Dissection</topic><topic>Neoplasm Recurrence, Local</topic><topic>Neoplasm Staging</topic><topic>Prospective Studies</topic><topic>Random Allocation</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgery of the upper aerodigestive tract</topic><topic>Tongue Neoplasms - mortality</topic><topic>Tongue Neoplasms - pathology</topic><topic>Tongue Neoplasms - surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fakih, Abdul R.</creatorcontrib><creatorcontrib>Rao, Raja S.</creatorcontrib><creatorcontrib>Borges, Anita M.</creatorcontrib><creatorcontrib>Patel, Ashraf R.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fakih, Abdul R.</au><au>Rao, Raja S.</au><au>Borges, Anita M.</au><au>Patel, Ashraf R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Elective versus therapeutic neck dissection in early carcinoma of the oral tongue</atitle><jtitle>The American journal of surgery</jtitle><addtitle>Am J Surg</addtitle><date>1989-10-01</date><risdate>1989</risdate><volume>158</volume><issue>4</issue><spage>309</spage><epage>313</epage><pages>309-313</pages><issn>0002-9610</issn><eissn>1879-1883</eissn><coden>AJSUAB</coden><abstract>A prospective, randomized trial was carried out to assess the value of elective versus therapeutic neck dissection in early squamous cell carcinoma of the oral tongue. Disease-free survival (median follow-up 20 months) was 52 percent versus 63 percent in patients who underwent hemiglossectomy alone and those who underwent hemiglossectomy and radical neck dissection, respectively (difference not statisti cally significant). Patients with a tumor depth of less than 4 mm did significantly better than those with a tumor depth of greater than 4 mm; they were also more likely to have uninvolved nodes at elective radical neck dissection compared with thost with a tumor depth of greater than 4 mm. However, when the survival rates of patients in the two treatment groups were compared with respect to a tumor depth of 4 mm, there was no significant difference between the hemiglossectomy and the hemiglossectomy and radical neck dissection groups. A policy of interval elective radical neck dissection only in those with a tumor depth of greater than 4 mm may optimize cure rates and avoid neck dissection in those unlikely to develop neck recurrence.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>2802032</pmid><doi>10.1016/0002-9610(89)90122-0</doi><tpages>5</tpages></addata></record> |
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| subjects | Adult Aged Biological and medical sciences Carcinoma, Squamous Cell - mortality Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - surgery Evaluation Studies as Topic Female Glossectomy Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics Humans Male Medical sciences Middle Aged Neck Dissection Neoplasm Recurrence, Local Neoplasm Staging Prospective Studies Random Allocation Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the upper aerodigestive tract Tongue Neoplasms - mortality Tongue Neoplasms - pathology Tongue Neoplasms - surgery |
| title | Elective versus therapeutic neck dissection in early carcinoma of the oral tongue |
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