Cross talk between angiotensin AT1 and alpha 1-adrenergic receptors: angiotensin II downregulates alpha 1a-adrenergic receptor subtype mRNA and density in neonatal rat cardiac myocytes

Signaling mediated by the angiotensin (Ang) II and alpha1-adrenergic receptor (alpha1-AR) pathways is important for cardiovascular homeostasis. However, it is unknown whether Ang II has any direct effect on alpha1-AR expression and signaling in cardiac myocytes. In the present study, we determined a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Circulation research 1997-09, Vol.81 (3), p.396-403
Hauptverfasser:	Li, H T, Long, C S, Gray, M O, Rokosh, D G, Honbo, N Y, Karliner, J S
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin II - pharmacology Animals Animals, Newborn Cells, Cultured Down-Regulation - drug effects Genes, fos - drug effects Myocardium - cytology Myocardium - metabolism Rats Receptor, Angiotensin, Type 1 Receptor, Angiotensin, Type 2 Receptors, Adrenergic, alpha-1 - genetics Receptors, Adrenergic, alpha-1 - metabolism Receptors, Angiotensin - metabolism RNA, Messenger - genetics RNA, Messenger - metabolism Signal Transduction
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!