Unethical Trials of Interventions to Reduce Perinatal Transmission of the Human Immunodeficiency Virus in Developing Countries

It has been almost three years since the Journal 1 published the results of AIDS Clinical Trials Group (ACTG) Study 076, the first randomized, controlled trial in which an intervention was proved to reduce the incidence of human immunodeficiency virus (HIV) infection. The antiretroviral drug zidovud...

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Veröffentlicht in:	The New England journal of medicine 1997-09, Vol.337 (12), p.853-856
Hauptverfasser:	Lurie, Peter, Wolfe, Sidney M
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Anti-HIV Agents - therapeutic use Bioethics Clinical trials Clinical Trials as Topic - methods Clinical Trials as Topic - standards Control Groups Developing Countries Drug therapy Ethical Relativism Ethics, Medical Federal Government Female HIV HIV Infections - prevention & control HIV Infections - therapy HIV Infections - transmission Human immunodeficiency virus Humans Infectious Disease Transmission, Vertical - prevention & control LDCs Medical ethics Placebos Population Pregnancy Pregnancy Complications, Infectious - drug therapy Pregnancy Complications, Infectious - therapy Pregnant Women Therapeutic Human Experimentation United States United States Public Health Service Zidovudine - therapeutic use
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