Computed tomography in depression: Association between ventricular size and psychopathology
The relationship between psychopathology and brain alterations, measured by computed tomography (CT), was investigated in 44 depressed patients. Comparisons of ventricle-brain ratio (VBR) between “endogenous” vs. “nonendoenous” subgroups, classified by six distinct diagnostic systems, revealed no si...
Gespeichert in:
| Veröffentlicht in: | Psychiatry research 1989-08, Vol.29 (2), p.221-230 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 230 |
|---|---|
| container_issue | 2 |
| container_start_page | 221 |
| container_title | Psychiatry research |
| container_volume | 29 |
| creator | Schlegel, Sabine Maier, Wolfgang Philipp, Michael Aldenhoff, Josef B. Heuser, Isabella Kretzschmar, Konrad Benkert, Otto |
| description | The relationship between psychopathology and brain alterations, measured by computed tomography (CT), was investigated in 44 depressed patients. Comparisons of ventricle-brain ratio (VBR) between “endogenous” vs. “nonendoenous” subgroups, classified by six distinct diagnostic systems, revealed no significant differences. The VBR and the width of the third ventricle correlated significantly with scores on the Brief Psychiatric Rating Scale, the Global Assessment Scale, the Bech-Rafaelsen Melancholia Scale, the Rating for Emotional Blunting, and the Scale for the Assessment of Negative Symptoms, but not with scores on the Hamilton Rating Scale for Depression and the Hamilton Rating Scale for Anxiety. Item analyses of the Bech-Rafaelsen Melancholia Scale revealed that retardation-related items were most significantly correlated with ventricular size. The wider diameter of the third ventricle in psychotic patients was associated with higher scores on retardation in the psychotic subgroup, whereas the greater distances of both Sylvian fissures showed no relationship to psychomotor retardation. No significant correlations were found between CT values and anxiety, suicidal impulses, somatic complaints, and sleep disturbances. |
| doi_str_mv | 10.1016/0165-1781(89)90037-1 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_79253328</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>0165178189900371</els_id><sourcerecordid>79253328</sourcerecordid><originalsourceid>FETCH-LOGICAL-c386t-e921dd157a2bbf5f3a802f30a0d1e2b48ab856bef3c0750603dceeae47e212473</originalsourceid><addsrcrecordid>eNp9kE1r3DAQhkVoSTcf_yAFHUpJD270YVtyDoWw9AsCuaSnHoQsjbMqtuVq5JTtr683u-yxh2EY3meG4SHkirOPnPH6Zqmq4Erza918aBiTquAnZMW1EoXiQr4iqyPyhpwh_mKMCd40p-RUqEbXjK_Iz3UcpjmDpzkO8SnZabOlYaQepgSIIY639A4xumDzMtAW8h-AkT7DmFNwc28TxfAXqB09nXDrNnGyeRP7-LS9IK872yNcHvo5-fHl8-P6W3H_8PX7-u6-cFLXuYBGcO95paxo267qpNVMdJJZ5jmIttS21VXdQicdUxWrmfQOwEKpQHBRKnlO3u_vTin-ngGzGQI66Hs7QpzRqEZUUgq9gOUedCkiJujMlMJg09ZwZnZOzU6Y2QkzujEvTg1f1t4e7s_tAP64dJC45O8OuUVn-y7Z0QU8YrWuRFnXC_Zpj8Hi4jlAMugCjA58SOCy8TH8_49_BBCUlQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>79253328</pqid></control><display><type>article</type><title>Computed tomography in depression: Association between ventricular size and psychopathology</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Schlegel, Sabine ; Maier, Wolfgang ; Philipp, Michael ; Aldenhoff, Josef B. ; Heuser, Isabella ; Kretzschmar, Konrad ; Benkert, Otto</creator><creatorcontrib>Schlegel, Sabine ; Maier, Wolfgang ; Philipp, Michael ; Aldenhoff, Josef B. ; Heuser, Isabella ; Kretzschmar, Konrad ; Benkert, Otto</creatorcontrib><description>The relationship between psychopathology and brain alterations, measured by computed tomography (CT), was investigated in 44 depressed patients. Comparisons of ventricle-brain ratio (VBR) between “endogenous” vs. “nonendoenous” subgroups, classified by six distinct diagnostic systems, revealed no significant differences. The VBR and the width of the third ventricle correlated significantly with scores on the Brief Psychiatric Rating Scale, the Global Assessment Scale, the Bech-Rafaelsen Melancholia Scale, the Rating for Emotional Blunting, and the Scale for the Assessment of Negative Symptoms, but not with scores on the Hamilton Rating Scale for Depression and the Hamilton Rating Scale for Anxiety. Item analyses of the Bech-Rafaelsen Melancholia Scale revealed that retardation-related items were most significantly correlated with ventricular size. The wider diameter of the third ventricle in psychotic patients was associated with higher scores on retardation in the psychotic subgroup, whereas the greater distances of both Sylvian fissures showed no relationship to psychomotor retardation. No significant correlations were found between CT values and anxiety, suicidal impulses, somatic complaints, and sleep disturbances.</description><identifier>ISSN: 0165-1781</identifier><identifier>EISSN: 1872-7123</identifier><identifier>DOI: 10.1016/0165-1781(89)90037-1</identifier><identifier>PMID: 2798601</identifier><identifier>CODEN: PSRSDR</identifier><language>eng</language><publisher>Shannon: Elsevier Ireland Ltd</publisher><subject>Adult ; Affective disorders ; Affective Disorders, Psychotic - diagnosis ; Biological and medical sciences ; Cerebral Ventricles - pathology ; computed tomography ; Depressive Disorder - diagnosis ; Depressive Disorder - psychology ; endogenous depression ; Female ; Humans ; Male ; Medical sciences ; melancholia ; Middle Aged ; Miscellaneous ; Neurocognitive Disorders - diagnosis ; Neurocognitive Disorders - psychology ; Psychiatric Status Rating Scales ; Psychology. Psychoanalysis. Psychiatry ; Psychometrics ; Psychopathology ; Psychopathology. Psychiatry ; rating scales ; Techniques and methods ; Tomography, X-Ray Computed</subject><ispartof>Psychiatry research, 1989-08, Vol.29 (2), p.221-230</ispartof><rights>1989</rights><rights>1990 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c386t-e921dd157a2bbf5f3a802f30a0d1e2b48ab856bef3c0750603dceeae47e212473</citedby><cites>FETCH-LOGICAL-c386t-e921dd157a2bbf5f3a802f30a0d1e2b48ab856bef3c0750603dceeae47e212473</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/0165178189900371$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=6852466$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2798601$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Schlegel, Sabine</creatorcontrib><creatorcontrib>Maier, Wolfgang</creatorcontrib><creatorcontrib>Philipp, Michael</creatorcontrib><creatorcontrib>Aldenhoff, Josef B.</creatorcontrib><creatorcontrib>Heuser, Isabella</creatorcontrib><creatorcontrib>Kretzschmar, Konrad</creatorcontrib><creatorcontrib>Benkert, Otto</creatorcontrib><title>Computed tomography in depression: Association between ventricular size and psychopathology</title><title>Psychiatry research</title><addtitle>Psychiatry Res</addtitle><description>The relationship between psychopathology and brain alterations, measured by computed tomography (CT), was investigated in 44 depressed patients. Comparisons of ventricle-brain ratio (VBR) between “endogenous” vs. “nonendoenous” subgroups, classified by six distinct diagnostic systems, revealed no significant differences. The VBR and the width of the third ventricle correlated significantly with scores on the Brief Psychiatric Rating Scale, the Global Assessment Scale, the Bech-Rafaelsen Melancholia Scale, the Rating for Emotional Blunting, and the Scale for the Assessment of Negative Symptoms, but not with scores on the Hamilton Rating Scale for Depression and the Hamilton Rating Scale for Anxiety. Item analyses of the Bech-Rafaelsen Melancholia Scale revealed that retardation-related items were most significantly correlated with ventricular size. The wider diameter of the third ventricle in psychotic patients was associated with higher scores on retardation in the psychotic subgroup, whereas the greater distances of both Sylvian fissures showed no relationship to psychomotor retardation. No significant correlations were found between CT values and anxiety, suicidal impulses, somatic complaints, and sleep disturbances.</description><subject>Adult</subject><subject>Affective disorders</subject><subject>Affective Disorders, Psychotic - diagnosis</subject><subject>Biological and medical sciences</subject><subject>Cerebral Ventricles - pathology</subject><subject>computed tomography</subject><subject>Depressive Disorder - diagnosis</subject><subject>Depressive Disorder - psychology</subject><subject>endogenous depression</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>melancholia</subject><subject>Middle Aged</subject><subject>Miscellaneous</subject><subject>Neurocognitive Disorders - diagnosis</subject><subject>Neurocognitive Disorders - psychology</subject><subject>Psychiatric Status Rating Scales</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychometrics</subject><subject>Psychopathology</subject><subject>Psychopathology. Psychiatry</subject><subject>rating scales</subject><subject>Techniques and methods</subject><subject>Tomography, X-Ray Computed</subject><issn>0165-1781</issn><issn>1872-7123</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1r3DAQhkVoSTcf_yAFHUpJD270YVtyDoWw9AsCuaSnHoQsjbMqtuVq5JTtr683u-yxh2EY3meG4SHkirOPnPH6Zqmq4Erza918aBiTquAnZMW1EoXiQr4iqyPyhpwh_mKMCd40p-RUqEbXjK_Iz3UcpjmDpzkO8SnZabOlYaQepgSIIY639A4xumDzMtAW8h-AkT7DmFNwc28TxfAXqB09nXDrNnGyeRP7-LS9IK872yNcHvo5-fHl8-P6W3H_8PX7-u6-cFLXuYBGcO95paxo267qpNVMdJJZ5jmIttS21VXdQicdUxWrmfQOwEKpQHBRKnlO3u_vTin-ngGzGQI66Hs7QpzRqEZUUgq9gOUedCkiJujMlMJg09ZwZnZOzU6Y2QkzujEvTg1f1t4e7s_tAP64dJC45O8OuUVn-y7Z0QU8YrWuRFnXC_Zpj8Hi4jlAMugCjA58SOCy8TH8_49_BBCUlQ</recordid><startdate>19890801</startdate><enddate>19890801</enddate><creator>Schlegel, Sabine</creator><creator>Maier, Wolfgang</creator><creator>Philipp, Michael</creator><creator>Aldenhoff, Josef B.</creator><creator>Heuser, Isabella</creator><creator>Kretzschmar, Konrad</creator><creator>Benkert, Otto</creator><general>Elsevier Ireland Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19890801</creationdate><title>Computed tomography in depression: Association between ventricular size and psychopathology</title><author>Schlegel, Sabine ; Maier, Wolfgang ; Philipp, Michael ; Aldenhoff, Josef B. ; Heuser, Isabella ; Kretzschmar, Konrad ; Benkert, Otto</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c386t-e921dd157a2bbf5f3a802f30a0d1e2b48ab856bef3c0750603dceeae47e212473</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>Adult</topic><topic>Affective disorders</topic><topic>Affective Disorders, Psychotic - diagnosis</topic><topic>Biological and medical sciences</topic><topic>Cerebral Ventricles - pathology</topic><topic>computed tomography</topic><topic>Depressive Disorder - diagnosis</topic><topic>Depressive Disorder - psychology</topic><topic>endogenous depression</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>melancholia</topic><topic>Middle Aged</topic><topic>Miscellaneous</topic><topic>Neurocognitive Disorders - diagnosis</topic><topic>Neurocognitive Disorders - psychology</topic><topic>Psychiatric Status Rating Scales</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychometrics</topic><topic>Psychopathology</topic><topic>Psychopathology. Psychiatry</topic><topic>rating scales</topic><topic>Techniques and methods</topic><topic>Tomography, X-Ray Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schlegel, Sabine</creatorcontrib><creatorcontrib>Maier, Wolfgang</creatorcontrib><creatorcontrib>Philipp, Michael</creatorcontrib><creatorcontrib>Aldenhoff, Josef B.</creatorcontrib><creatorcontrib>Heuser, Isabella</creatorcontrib><creatorcontrib>Kretzschmar, Konrad</creatorcontrib><creatorcontrib>Benkert, Otto</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Psychiatry research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schlegel, Sabine</au><au>Maier, Wolfgang</au><au>Philipp, Michael</au><au>Aldenhoff, Josef B.</au><au>Heuser, Isabella</au><au>Kretzschmar, Konrad</au><au>Benkert, Otto</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Computed tomography in depression: Association between ventricular size and psychopathology</atitle><jtitle>Psychiatry research</jtitle><addtitle>Psychiatry Res</addtitle><date>1989-08-01</date><risdate>1989</risdate><volume>29</volume><issue>2</issue><spage>221</spage><epage>230</epage><pages>221-230</pages><issn>0165-1781</issn><eissn>1872-7123</eissn><coden>PSRSDR</coden><abstract>The relationship between psychopathology and brain alterations, measured by computed tomography (CT), was investigated in 44 depressed patients. Comparisons of ventricle-brain ratio (VBR) between “endogenous” vs. “nonendoenous” subgroups, classified by six distinct diagnostic systems, revealed no significant differences. The VBR and the width of the third ventricle correlated significantly with scores on the Brief Psychiatric Rating Scale, the Global Assessment Scale, the Bech-Rafaelsen Melancholia Scale, the Rating for Emotional Blunting, and the Scale for the Assessment of Negative Symptoms, but not with scores on the Hamilton Rating Scale for Depression and the Hamilton Rating Scale for Anxiety. Item analyses of the Bech-Rafaelsen Melancholia Scale revealed that retardation-related items were most significantly correlated with ventricular size. The wider diameter of the third ventricle in psychotic patients was associated with higher scores on retardation in the psychotic subgroup, whereas the greater distances of both Sylvian fissures showed no relationship to psychomotor retardation. No significant correlations were found between CT values and anxiety, suicidal impulses, somatic complaints, and sleep disturbances.</abstract><cop>Shannon</cop><pub>Elsevier Ireland Ltd</pub><pmid>2798601</pmid><doi>10.1016/0165-1781(89)90037-1</doi><tpages>10</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0165-1781 |
| ispartof | Psychiatry research, 1989-08, Vol.29 (2), p.221-230 |
| issn | 0165-1781 1872-7123 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_79253328 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adult Affective disorders Affective Disorders, Psychotic - diagnosis Biological and medical sciences Cerebral Ventricles - pathology computed tomography Depressive Disorder - diagnosis Depressive Disorder - psychology endogenous depression Female Humans Male Medical sciences melancholia Middle Aged Miscellaneous Neurocognitive Disorders - diagnosis Neurocognitive Disorders - psychology Psychiatric Status Rating Scales Psychology. Psychoanalysis. Psychiatry Psychometrics Psychopathology Psychopathology. Psychiatry rating scales Techniques and methods Tomography, X-Ray Computed |
| title | Computed tomography in depression: Association between ventricular size and psychopathology |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-28T11%3A45%3A26IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Computed%20tomography%20in%20depression:%20Association%20between%20ventricular%20size%20and%20psychopathology&rft.jtitle=Psychiatry%20research&rft.au=Schlegel,%20Sabine&rft.date=1989-08-01&rft.volume=29&rft.issue=2&rft.spage=221&rft.epage=230&rft.pages=221-230&rft.issn=0165-1781&rft.eissn=1872-7123&rft.coden=PSRSDR&rft_id=info:doi/10.1016/0165-1781(89)90037-1&rft_dat=%3Cproquest_cross%3E79253328%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=79253328&rft_id=info:pmid/2798601&rft_els_id=0165178189900371&rfr_iscdi=true |