PP2Cγ: a human protein phosphatase with a unique acidic domain

We have cloned a novel cDNA from human skeletal muscle which encodes a protein phosphatase with a unique acidic domain. It is 34% identical to mammalian PP2Cα and PP2Cβ, and we call it PP2Cγ. It more closely resembles PP2Cs from Paramecium tetraurelia and Schizosaccharomyces pombe than mammalian PP2...

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Veröffentlicht in:	FEBS letters 1997-08, Vol.412 (3), p.415-419
Hauptverfasser:	Travis, Sue M, Welsh, Michael J
Format:	Artikel
Sprache:	eng
Schlagworte:	acidic domain Amino Acid Sequence Animals cDNA Cloning, Molecular Enzyme Activation Humans Mice Molecular Sequence Data Organ Specificity Paramecium - enzymology Paramecium - genetics Phosphoprotein Phosphatases - chemistry Phosphoprotein Phosphatases - genetics Phosphoprotein Phosphatases - isolation & purification Phylogeny Protein Phosphatase 2 Protein Phosphatase 2C Protein phosphorylation Protein Structure, Tertiary Saccharomyces cerevisiae Proteins Sequence Analysis, DNA
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