Effects of retinoic acid on a new human erythromegakaryocytic cell line AP-217

We have characterized a new human cell line AP-217, derived from the peripheral blood of a patient with chronic myeloid leukemia in blastic crisis. The analysis of cell surface antigens and ploidy showed that AP-217 was an erythro-megakaryocytic cell line. The effects of inducers of differentiation...

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Veröffentlicht in:	Leukemia research 1997-06, Vol.21 (6), p.529-537
Hauptverfasser:	MOSSUZ, P, PRANDINI, M. H, LEROUX, D, VALIRON, O, SCHWEITZER, A, SASSETTI, B, KOLODIE, L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antigens, Surface - metabolism Biological and medical sciences Blotting, Northern Cell Differentiation - drug effects Cell Division - drug effects Cloning, Molecular Erythrocytes - drug effects Erythrocytes - metabolism Erythrocytes - pathology Globins - genetics Hematologic and hematopoietic diseases Hemoglobins - biosynthesis Humans Isotretinoin - pharmacology Karyotyping Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Male Medical sciences Megakaryocytes - drug effects Megakaryocytes - metabolism Megakaryocytes - pathology Polymerase Chain Reaction Tumor Cells, Cultured
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