Intratesticular feedback mechanisms in the regulation of steroid profiles in the frog, Rana esculenta
Testosterone (T), 5α-dihydrotestosterone (DHT), estradiol-17β (E), and progesterone (P) were measured in the plasma of the frog, Rana esculenta, during the annual cycle. Moreover, in vitro experiments were carried out in order to investigate the local regulation of steroidogenesis. Testosterone and...
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| Veröffentlicht in: | General and comparative endocrinology 1989-09, Vol.75 (3), p.335-342 |
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| container_title | General and comparative endocrinology |
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| creator | Fasano, Silvia Minucci, Sergio Di Matteo, Loredana D'Antonio, Mauro Pierantoni, Riccardo |
| description | Testosterone (T), 5α-dihydrotestosterone (DHT), estradiol-17β (E), and progesterone (P) were measured in the plasma of the frog,
Rana esculenta, during the annual cycle. Moreover,
in vitro experiments were carried out in order to investigate the local regulation of steroidogenesis. Testosterone and DHT showed high values during autumn and early spring and had a
T
DHT
ratio which increased during summer, while E peaked in midspring, remaining at detectable values thereafter. Progesterone increased in autumn, winter, and spring.
In vitro incubations of minced testes showed that E, stimulated by pituitary factors, inhibited androgen synthesis while T did not. Our results indicate that paracrine and/or autocrine mechanisms operate in the frog testis to regulate annual steroid profiles. |
| doi_str_mv | 10.1016/0016-6480(89)90167-6 |
| format | Article |
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Rana esculenta, during the annual cycle. Moreover,
in vitro experiments were carried out in order to investigate the local regulation of steroidogenesis. Testosterone and DHT showed high values during autumn and early spring and had a
T
DHT
ratio which increased during summer, while E peaked in midspring, remaining at detectable values thereafter. Progesterone increased in autumn, winter, and spring.
In vitro incubations of minced testes showed that E, stimulated by pituitary factors, inhibited androgen synthesis while T did not. Our results indicate that paracrine and/or autocrine mechanisms operate in the frog testis to regulate annual steroid profiles.</description><identifier>ISSN: 0016-6480</identifier><identifier>EISSN: 1095-6840</identifier><identifier>DOI: 10.1016/0016-6480(89)90167-6</identifier><identifier>PMID: 2792721</identifier><identifier>CODEN: GCENA5</identifier><language>eng</language><publisher>San Diego, CA: Elsevier Inc</publisher><subject>Animals ; Biological and medical sciences ; Dihydrotestosterone - blood ; Estradiol - blood ; Feedback ; Fundamental and applied biological sciences. Psychology ; Gonadal Steroid Hormones - blood ; Male ; Progesterone - blood ; Rana esculenta ; Rana esculenta - physiology ; Seasons ; Steroid hormones. Cholecalciferol derivatives ; Testis - physiology ; Testosterone - blood ; Vertebrates: endocrinology</subject><ispartof>General and comparative endocrinology, 1989-09, Vol.75 (3), p.335-342</ispartof><rights>1989</rights><rights>1990 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c483t-831279d7b7657e12fff14ae64440d3d9aa9af67a8c8092765ff0b1058c86c5303</citedby><cites>FETCH-LOGICAL-c483t-831279d7b7657e12fff14ae64440d3d9aa9af67a8c8092765ff0b1058c86c5303</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/0016648089901676$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=6621671$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2792721$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fasano, Silvia</creatorcontrib><creatorcontrib>Minucci, Sergio</creatorcontrib><creatorcontrib>Di Matteo, Loredana</creatorcontrib><creatorcontrib>D'Antonio, Mauro</creatorcontrib><creatorcontrib>Pierantoni, Riccardo</creatorcontrib><title>Intratesticular feedback mechanisms in the regulation of steroid profiles in the frog, Rana esculenta</title><title>General and comparative endocrinology</title><addtitle>Gen Comp Endocrinol</addtitle><description>Testosterone (T), 5α-dihydrotestosterone (DHT), estradiol-17β (E), and progesterone (P) were measured in the plasma of the frog,
Rana esculenta, during the annual cycle. Moreover,
in vitro experiments were carried out in order to investigate the local regulation of steroidogenesis. Testosterone and DHT showed high values during autumn and early spring and had a
T
DHT
ratio which increased during summer, while E peaked in midspring, remaining at detectable values thereafter. Progesterone increased in autumn, winter, and spring.
In vitro incubations of minced testes showed that E, stimulated by pituitary factors, inhibited androgen synthesis while T did not. Our results indicate that paracrine and/or autocrine mechanisms operate in the frog testis to regulate annual steroid profiles.</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Dihydrotestosterone - blood</subject><subject>Estradiol - blood</subject><subject>Feedback</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Gonadal Steroid Hormones - blood</subject><subject>Male</subject><subject>Progesterone - blood</subject><subject>Rana esculenta</subject><subject>Rana esculenta - physiology</subject><subject>Seasons</subject><subject>Steroid hormones. Cholecalciferol derivatives</subject><subject>Testis - physiology</subject><subject>Testosterone - blood</subject><subject>Vertebrates: endocrinology</subject><issn>0016-6480</issn><issn>1095-6840</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkdFLHDEQxkNR9Kr9DyrkQUoLXU12s0n2RSjS2gNBEH0Oc9mJpt3NapIT_O-b7R33qC8Zhvnl45tvCPnM2RlnXJ6z8lRSaPZVd9-60qhKfiALzrq2klqwPbLYIYfkY0p_GGNtI_kBOahVV6uaLwguQ46QMWVv1wNE6hD7Fdi_dET7CMGnMVEfaH5EGvGhINlPgU6Opoxx8j19ipPzA-4oF6eH7_QWAlBMRRNDhmOy72BI-Glbj8j9r593l7-r65ur5eWP68oK3eRKN7wY69VKyVYhr51zXABKIQTrm74D6MBJBdpqVvzL1jm24qwtvbRtw5oj8mWjW0w9r8tSZvTJ4jBAwGmdTNm6UVrJd0HeiiKrugKKDWjjlFJEZ56iHyG-Gs7MfAYzZ2zmjI3uzP8zmFn_ZKu_Xo3Y7z5tcy_z0-0ckoXBRQjWpx0mZV10Zuxig2EJ7cVjNMl6DBZ7H9Fm00_-bR__ABf8o4g</recordid><startdate>19890901</startdate><enddate>19890901</enddate><creator>Fasano, Silvia</creator><creator>Minucci, Sergio</creator><creator>Di Matteo, Loredana</creator><creator>D'Antonio, Mauro</creator><creator>Pierantoni, Riccardo</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>19890901</creationdate><title>Intratesticular feedback mechanisms in the regulation of steroid profiles in the frog, Rana esculenta</title><author>Fasano, Silvia ; Minucci, Sergio ; Di Matteo, Loredana ; D'Antonio, Mauro ; Pierantoni, Riccardo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c483t-831279d7b7657e12fff14ae64440d3d9aa9af67a8c8092765ff0b1058c86c5303</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Dihydrotestosterone - blood</topic><topic>Estradiol - blood</topic><topic>Feedback</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Gonadal Steroid Hormones - blood</topic><topic>Male</topic><topic>Progesterone - blood</topic><topic>Rana esculenta</topic><topic>Rana esculenta - physiology</topic><topic>Seasons</topic><topic>Steroid hormones. Cholecalciferol derivatives</topic><topic>Testis - physiology</topic><topic>Testosterone - blood</topic><topic>Vertebrates: endocrinology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fasano, Silvia</creatorcontrib><creatorcontrib>Minucci, Sergio</creatorcontrib><creatorcontrib>Di Matteo, Loredana</creatorcontrib><creatorcontrib>D'Antonio, Mauro</creatorcontrib><creatorcontrib>Pierantoni, Riccardo</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>General and comparative endocrinology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fasano, Silvia</au><au>Minucci, Sergio</au><au>Di Matteo, Loredana</au><au>D'Antonio, Mauro</au><au>Pierantoni, Riccardo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Intratesticular feedback mechanisms in the regulation of steroid profiles in the frog, Rana esculenta</atitle><jtitle>General and comparative endocrinology</jtitle><addtitle>Gen Comp Endocrinol</addtitle><date>1989-09-01</date><risdate>1989</risdate><volume>75</volume><issue>3</issue><spage>335</spage><epage>342</epage><pages>335-342</pages><issn>0016-6480</issn><eissn>1095-6840</eissn><coden>GCENA5</coden><abstract>Testosterone (T), 5α-dihydrotestosterone (DHT), estradiol-17β (E), and progesterone (P) were measured in the plasma of the frog,
Rana esculenta, during the annual cycle. Moreover,
in vitro experiments were carried out in order to investigate the local regulation of steroidogenesis. Testosterone and DHT showed high values during autumn and early spring and had a
T
DHT
ratio which increased during summer, while E peaked in midspring, remaining at detectable values thereafter. Progesterone increased in autumn, winter, and spring.
In vitro incubations of minced testes showed that E, stimulated by pituitary factors, inhibited androgen synthesis while T did not. Our results indicate that paracrine and/or autocrine mechanisms operate in the frog testis to regulate annual steroid profiles.</abstract><cop>San Diego, CA</cop><pub>Elsevier Inc</pub><pmid>2792721</pmid><doi>10.1016/0016-6480(89)90167-6</doi><tpages>8</tpages></addata></record> |
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| ispartof | General and comparative endocrinology, 1989-09, Vol.75 (3), p.335-342 |
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| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Animals Biological and medical sciences Dihydrotestosterone - blood Estradiol - blood Feedback Fundamental and applied biological sciences. Psychology Gonadal Steroid Hormones - blood Male Progesterone - blood Rana esculenta Rana esculenta - physiology Seasons Steroid hormones. Cholecalciferol derivatives Testis - physiology Testosterone - blood Vertebrates: endocrinology |
| title | Intratesticular feedback mechanisms in the regulation of steroid profiles in the frog, Rana esculenta |
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