Structure and distribution of the Notch protein in developing Drosophila

Antibodies to Notch show that it is a stable, high-molecular-weight transmembrane glycoprotein, with epidermal growth factor (EGF)-like elements exposed on the cell surface. The protein is phosphorylated variably on serines of the cytoplasmic domain. Individual Notch polypeptide chains appear to be...

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Veröffentlicht in:	Genes & development 1989-08, Vol.3 (8), p.1113-1129
Hauptverfasser:	Kidd, S, Baylies, M K, Gasic, G P, Young, M W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Differentiation Cell Membrane - metabolism Diptera Drosophila Drosophila - genetics Drosophila - growth & development Drosophila - metabolism Drosophilidae Epidermal Growth Factor - metabolism Membrane Glycoproteins - genetics Membrane Glycoproteins - metabolism Molecular Weight Mutation Phosphorylation Tissue Distribution
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