Effect of Supplemental Oral l-Arginine on Exercise Capacity in Patients With Stable Angina Pectoris

A randomized, double-blind, placebo-controlled study in patients with clinical symptoms of stable angina pectoris and healed myocardial infarction (n = 22) has shown that oral supplementation with L-arginine (6 g/day for 3 days) increases exercise capacity (tested on a Marquette case 12 treadmill ac...

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Veröffentlicht in:The American journal of cardiology 1997-08, Vol.80 (3), p.331-333
Hauptverfasser: Ceremużyński, Leszek, Chamiec, Tomasz, Herbaczyńska-Cedro, Krystyna
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container_end_page 333
container_issue 3
container_start_page 331
container_title The American journal of cardiology
container_volume 80
creator Ceremużyński, Leszek
Chamiec, Tomasz
Herbaczyńska-Cedro, Krystyna
description A randomized, double-blind, placebo-controlled study in patients with clinical symptoms of stable angina pectoris and healed myocardial infarction (n = 22) has shown that oral supplementation with L-arginine (6 g/day for 3 days) increases exercise capacity (tested on a Marquette case 12 treadmill according to the modified Bruce protocol). Results suggest that the inefficient L-arginine/nitric oxide system contributes to limitation of myocardial perfusion and/or peripheral vasodilation during maximum exercise in patients with stable angina pectoris.
doi_str_mv 10.1016/S0002-9149(97)00354-8
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source MEDLINE; Access via ScienceDirect (Elsevier)
subjects Adult
Aged
Angina pectoris
Angina Pectoris - physiopathology
Arginine - pharmacology
Biological and medical sciences
Double-Blind Method
Drug therapy
Exercise
Exercise Tolerance - drug effects
Female
General and cellular metabolism. Vitamins
Humans
Male
Medical research
Medical sciences
Middle Aged
Pharmacology. Drug treatments
Vasodilation - drug effects
title Effect of Supplemental Oral l-Arginine on Exercise Capacity in Patients With Stable Angina Pectoris
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