Long-term study of patients with severe forms of Sjögren syndrome and/or myoepithelial sialadenitis

It is well known that the incidence of malignant lymphomas (non-Hodgkin type) is increased in patients with Sjögren's syndrome. The occurrence of malignant diseases was retrospectively studied in 62 patients. In the course of the disease two patients developed a non-Hodgkin lymphoma, one patien...

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Veröffentlicht in:Laryngo- rhino- otologie 1989-08, Vol.68 (8), p.442-444
Hauptverfasser: Brauneis, J, Schröder, M, Laskawi, R
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container_title Laryngo- rhino- otologie
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creator Brauneis, J
Schröder, M
Laskawi, R
description It is well known that the incidence of malignant lymphomas (non-Hodgkin type) is increased in patients with Sjögren's syndrome. The occurrence of malignant diseases was retrospectively studied in 62 patients. In the course of the disease two patients developed a non-Hodgkin lymphoma, one patient developed a transitional-cell carcinoma located in the nasopharynx and three patients developed a squamous-cell carcinoma located in the salivary glands. The large quantity of epithelial carcinomas seems to be remarkable, especially compared with the number of non-Hodgkin lymphomas. It might be possible that early surgical treatment of persistent or progressive swelling of the salivary glands helps to prevent the occurrence of malignant lymphoma in patients with known myoepithelial sialadenitis.
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source MEDLINE; Thieme Connect Journals
subjects Carcinoma, Squamous Cell - surgery
Carcinoma, Transitional Cell - surgery
Follow-Up Studies
Humans
Lymphoma, Non-Hodgkin - surgery
Nasopharyngeal Neoplasms - surgery
Parotid Neoplasms - surgery
Risk Factors
Salivary Gland Diseases - complications
Salivary Gland Neoplasms - surgery
Sialadenitis - complications
Sjogren's Syndrome - complications
title Long-term study of patients with severe forms of Sjögren syndrome and/or myoepithelial sialadenitis
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