Distribution of desmoplakin in normal cultured human keratinocytes and in basal cell carcinoma cells

In cultured human keratinocytes (NHEK) maintained in medium containing low levels of Ca2+ (0.04 mM) desmoplakin is a component of certain electron‐dense bodies in the cytoplasm. These bodies are associated with bundles of intermediate filaments. Upon elevation of the level of Ca2+ in the culture med...

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Veröffentlicht in:	Cell motility and the cytoskeleton 1989, Vol.13 (3), p.181-194
Hauptverfasser:	Jones, Jonathan C. R., Grelling, Kent A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blotting, Western Calcium - metabolism Carcinoma, Basal Cell - analysis Carcinoma, Basal Cell - ultrastructure Cell structures and functions Cells, Cultured Cytoskeletal Proteins - analysis Cytoskeleton, cytoplasm. Intracellular movements Desmoplakins desmosomes Desmosomes - analysis Epidermis - analysis Epidermis - ultrastructure Fluorescent Antibody Technique Fundamental and applied biological sciences. Psychology Humans Intermediate Filaments - analysis keratinocytes Keratins Microscopy, Electron Molecular and cellular biology tumor cells Tumor Cells, Cultured
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