Exercise capacity during the first year after cardiac transplantation

Few data are available examining the influence of perioperative clinical parameters on exercise capacity after cardiac transplantation. Accordingly, 40 patients were studied by metabolic exercise testing early (1 to 3 months) and late (6 to 12 months) after cardiac transplantation. Various clinical...

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Veröffentlicht in:The American journal of cardiology 1989-09, Vol.64 (10), p.642-645
Hauptverfasser: Labovitz, Arthur J., Drimmer, Ami M., McBride, Lawrence R., Pennington, D.Glenn, Willman, Vallee L., Miller, Leslie W.
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container_issue 10
container_start_page 642
container_title The American journal of cardiology
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creator Labovitz, Arthur J.
Drimmer, Ami M.
McBride, Lawrence R.
Pennington, D.Glenn
Willman, Vallee L.
Miller, Leslie W.
description Few data are available examining the influence of perioperative clinical parameters on exercise capacity after cardiac transplantation. Accordingly, 40 patients were studied by metabolic exercise testing early (1 to 3 months) and late (6 to 12 months) after cardiac transplantation. Various clinical parameters, including congestive heart failure class, length of hospital stay, age, cold ischemic time and histologic evidence of refection were correlated with exercise capacity after transplantation. As expected, peak exercise capacity correlated inversely with both age and length of hospital stay. There was no correlation with preoperative congestive heart failure class or heart rate at rest. Interestingly, there was a statistically significant correlation between cold ischemic time and exercise capacity after transplantation. In addition, increased episodes of rejection during the first 6 months after transplantation resulted in statistically lower exercise capacity at 6 to 12 months after the operation. Thus, ischemic damage during transport of the donor organs and subclinical damage during early rejection may affect clinical status after heart transplantation and may only be apparent during increased physical demand such as exercise.
doi_str_mv 10.1016/0002-9149(89)90494-3
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subjects Adult
Biological and medical sciences
Electrocardiography
Exercise
Exercise Test
Female
Graft Rejection
Heart Rate
Heart Transplantation
Humans
Length of Stay
Male
Medical sciences
Physical Exertion
Postoperative Period
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the heart
title Exercise capacity during the first year after cardiac transplantation
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