Influence of ovariectomy, estradiol and progesterone on the behavior of mice in an experimental model of depression

In the tail suspension test (an animal model of depression) the duration of immobility during the 6 min of observation was 56.84±6.54 sec in sham-ovariectomized mice and 113.11±7.86 sec 30–32 days after ovariectomy. Estradiol (10, 100 or 1,000 μ/kg) and progesterone (50, 1,000 or 10,000 μ/kg), subcu...

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Veröffentlicht in:	Physiology & behavior 1989-05, Vol.45 (5), p.1067-1068
Hauptverfasser:	Bernardi, M., Vergoni, A.V., Sandrini, M., Tagliavini, S., Bertolini, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Behavior, Animal - drug effects Behavioral psychophysiology Biological and medical sciences Depression Depression - drug therapy Desipramine - pharmacology Disease Models, Animal Dose-Response Relationship, Drug Estradiol Estradiol - pharmacology Female Fundamental and applied biological sciences. Psychology Mice Miscellaneous Mouse Ovariectomy Progesterone Progesterone - pharmacology Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Tail suspension test
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