Effect of high NaCl intake on Na+ and K+ transport in the rabbit distal convoluted tubule

Morphological studies have demonstrated that a chronic increase in distal Na+ delivery causes hypertrophy of the distal convoluted tubule (DCT). To examine whether high NaCl-intake also causes functional changes in the well defined DCT, we measured transmural voltage (VT), lumen-to-bath Na+ flux (JN...

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Veröffentlicht in:	Pflügers Archiv 1989-09, Vol.414 (5), p.500-508
Hauptverfasser:	SHIMIZU, T, YOSHITOMI, K, TANIGUCHI, J, IMAI, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldosterone - blood Animals Biological and medical sciences Biological Transport - drug effects Fundamental and applied biological sciences. Psychology In Vitro Techniques Kidney Tubules - drug effects Kidney Tubules, Distal - drug effects Kidney Tubules, Distal - metabolism Male Potassium - metabolism Rabbits Renin - blood Sodium - metabolism Sodium Chloride - administration & dosage Sodium-Potassium-Exchanging ATPase - metabolism Vertebrates: urinary system
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