Linkage Analysis of Candidate Regions for Coeliac Disease Genes

A strong HLA association is seen in coeliac disease [specifically to the DQ(α1*0501,β1*0201 heterodimer], but this cannot entirely account for the increased risk seen in relatives of affected cases. One or more genes at HLA-unlinked loci also predispose to coeliac disease and are probably stronger d...

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Veröffentlicht in:	Human molecular genetics 1997-08, Vol.6 (8), p.1335-1339
Hauptverfasser:	Houlston, R. S., Tomlinson, I. P. M., Ford, D., Seal, S., Marossy, A. M., Ferguson, A., Holmes, G. K. T., Hosie, K. B., Howdle, P. D., Jewell, D. P., Godkin, A., Kerr, G. D., Kumar, P., Logan, R. F. A., Love, A. H. G., Johnston, S., Marsh, M. N., Mitton, S., O'Donoghue, D., Roberts, A., Walker-Smith, J. A., Stratton, M. F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Celiac Disease - genetics Chromosome Mapping Chromosomes, Human, Pair 11 Chromosomes, Human, Pair 15 Chromosomes, Human, Pair 19 Chromosomes, Human, Pair 22 Chromosomes, Human, Pair 3 Chromosomes, Human, Pair 5 Chromosomes, Human, Pair 6 Chromosomes, Human, Pair 7 Female Gastroenterology. Liver. Pancreas. Abdomen Genetic Linkage HLA-DQ Antigens - genetics Humans Male Medical sciences Other diseases. Semiology Pedigree Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
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