Extraosseous Ewing's sarcoma. A study of 42 cases
Fifty patients at the Mayo Clinic (Rochester, MN) from 1935 to 1985 met the histologic criteria for extraosseous Ewing's sarcoma. Forty‐two had soft tissue primaries without bony involvement and formed the basis for this retrospective study of the clinical behavior and management of extraosseou...
Gespeichert in:
| Veröffentlicht in: | Cancer 1989-10, Vol.64 (7), p.1548-1553 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1553 |
|---|---|
| container_issue | 7 |
| container_start_page | 1548 |
| container_title | Cancer |
| container_volume | 64 |
| creator | Rud, Nathan P. Reiman, Herbert M. Pritchard, Douglas J. Frassica, Frank J. Smithson, William A. |
| description | Fifty patients at the Mayo Clinic (Rochester, MN) from 1935 to 1985 met the histologic criteria for extraosseous Ewing's sarcoma. Forty‐two had soft tissue primaries without bony involvement and formed the basis for this retrospective study of the clinical behavior and management of extraosseous Ewing's sarcoma. There were 19 male and 23 female patients (mean age, 22 years). Metastases were documented in 30 of the patients, six at the time of presentation and 24 occurring up to 11 years later, most commonly to lungs or bone. Three patients were lost to follow‐up. Sixteen of 35 patients (46%) had local recurrence. Overall survival was 15 of 39 (38.5%) at 5 years. Decreased survival was noted with pelvic tumors, incomplete resections, and presence of metastatic disease, whereas increased survival was associated with wide surgical resection with negative microscopic margins, adjuvant local radiation therapy, and presentation since 1970 (48% 5‐year survival compared with 28% before 1970). |
| doi_str_mv | 10.1002/1097-0142(19891001)64:7<1548::AID-CNCR2820640733>3.0.CO;2-W |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_79206953</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>79206953</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5353-be27c3ca92c8a3cdad3142b47d2cb40281137bb369ee7424b1f7e9c5b70613a13</originalsourceid><addsrcrecordid>eNqVkF9LwzAUxYMoc04_gtAn_zy0Jrlp004RRp06GA5EmeDDJU1TmWzrbDbmvr0pmwN9EHwKN-fec8_9EZIyGjBK-QWjifQpE_yMJXHivth5JNryioUibrc7vRs_fUgfecxpJKgEuIaABungkvvDHdLcTu-SJqU09kMBL_vkwNp3V0oeQoM0uJQRY2GTsO7nvFKltaZcWK-7HE3fTq1nVaXLiQq8jmfni3zllYUnuKeVNfaQ7BVqbM3R5m2R59vuU3rv9wd3vbTT93UIIfiZ4VKDVgnXsQKdqxxcpkzInOtMUB4zBjLLIEqMkYKLjBXSJDrMJI0YKAYtcrL2nVXlx8LYOU5GVpvxWE3rrCgTd38Sgmt8XTfqyt1RmQJn1WiiqhUyijVQrJFgjQS_gWIkUGINFNEBxZ9AEZBiOkCOQ-d-vImxyCYm33pvCDq9WOvL0dis_rf6z82_FPgCNsiQ3w</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>79206953</pqid></control><display><type>article</type><title>Extraosseous Ewing's sarcoma. A study of 42 cases</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Rud, Nathan P. ; Reiman, Herbert M. ; Pritchard, Douglas J. ; Frassica, Frank J. ; Smithson, William A.</creator><creatorcontrib>Rud, Nathan P. ; Reiman, Herbert M. ; Pritchard, Douglas J. ; Frassica, Frank J. ; Smithson, William A.</creatorcontrib><description>Fifty patients at the Mayo Clinic (Rochester, MN) from 1935 to 1985 met the histologic criteria for extraosseous Ewing's sarcoma. Forty‐two had soft tissue primaries without bony involvement and formed the basis for this retrospective study of the clinical behavior and management of extraosseous Ewing's sarcoma. There were 19 male and 23 female patients (mean age, 22 years). Metastases were documented in 30 of the patients, six at the time of presentation and 24 occurring up to 11 years later, most commonly to lungs or bone. Three patients were lost to follow‐up. Sixteen of 35 patients (46%) had local recurrence. Overall survival was 15 of 39 (38.5%) at 5 years. Decreased survival was noted with pelvic tumors, incomplete resections, and presence of metastatic disease, whereas increased survival was associated with wide surgical resection with negative microscopic margins, adjuvant local radiation therapy, and presentation since 1970 (48% 5‐year survival compared with 28% before 1970).</description><identifier>ISSN: 0008-543X</identifier><identifier>EISSN: 1097-0142</identifier><identifier>DOI: 10.1002/1097-0142(19891001)64:7<1548::AID-CNCR2820640733>3.0.CO;2-W</identifier><identifier>PMID: 2776115</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Adolescent ; Adult ; Aged ; Back ; Child ; Child, Preschool ; Combined Modality Therapy ; Female ; Foot ; Humans ; Infant ; Male ; Middle Aged ; Minnesota ; Pelvis ; Retrospective Studies ; Sarcoma, Ewing - mortality ; Sarcoma, Ewing - pathology ; Sarcoma, Ewing - therapy ; Soft Tissue Neoplasms - mortality ; Soft Tissue Neoplasms - pathology ; Soft Tissue Neoplasms - therapy ; Thigh</subject><ispartof>Cancer, 1989-10, Vol.64 (7), p.1548-1553</ispartof><rights>Copyright © 1989 American Cancer Society</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c5353-be27c3ca92c8a3cdad3142b47d2cb40281137bb369ee7424b1f7e9c5b70613a13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2776115$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rud, Nathan P.</creatorcontrib><creatorcontrib>Reiman, Herbert M.</creatorcontrib><creatorcontrib>Pritchard, Douglas J.</creatorcontrib><creatorcontrib>Frassica, Frank J.</creatorcontrib><creatorcontrib>Smithson, William A.</creatorcontrib><title>Extraosseous Ewing's sarcoma. A study of 42 cases</title><title>Cancer</title><addtitle>Cancer</addtitle><description>Fifty patients at the Mayo Clinic (Rochester, MN) from 1935 to 1985 met the histologic criteria for extraosseous Ewing's sarcoma. Forty‐two had soft tissue primaries without bony involvement and formed the basis for this retrospective study of the clinical behavior and management of extraosseous Ewing's sarcoma. There were 19 male and 23 female patients (mean age, 22 years). Metastases were documented in 30 of the patients, six at the time of presentation and 24 occurring up to 11 years later, most commonly to lungs or bone. Three patients were lost to follow‐up. Sixteen of 35 patients (46%) had local recurrence. Overall survival was 15 of 39 (38.5%) at 5 years. Decreased survival was noted with pelvic tumors, incomplete resections, and presence of metastatic disease, whereas increased survival was associated with wide surgical resection with negative microscopic margins, adjuvant local radiation therapy, and presentation since 1970 (48% 5‐year survival compared with 28% before 1970).</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Back</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Combined Modality Therapy</subject><subject>Female</subject><subject>Foot</subject><subject>Humans</subject><subject>Infant</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Minnesota</subject><subject>Pelvis</subject><subject>Retrospective Studies</subject><subject>Sarcoma, Ewing - mortality</subject><subject>Sarcoma, Ewing - pathology</subject><subject>Sarcoma, Ewing - therapy</subject><subject>Soft Tissue Neoplasms - mortality</subject><subject>Soft Tissue Neoplasms - pathology</subject><subject>Soft Tissue Neoplasms - therapy</subject><subject>Thigh</subject><issn>0008-543X</issn><issn>1097-0142</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkF9LwzAUxYMoc04_gtAn_zy0Jrlp004RRp06GA5EmeDDJU1TmWzrbDbmvr0pmwN9EHwKN-fec8_9EZIyGjBK-QWjifQpE_yMJXHivth5JNryioUibrc7vRs_fUgfecxpJKgEuIaABungkvvDHdLcTu-SJqU09kMBL_vkwNp3V0oeQoM0uJQRY2GTsO7nvFKltaZcWK-7HE3fTq1nVaXLiQq8jmfni3zllYUnuKeVNfaQ7BVqbM3R5m2R59vuU3rv9wd3vbTT93UIIfiZ4VKDVgnXsQKdqxxcpkzInOtMUB4zBjLLIEqMkYKLjBXSJDrMJI0YKAYtcrL2nVXlx8LYOU5GVpvxWE3rrCgTd38Sgmt8XTfqyt1RmQJn1WiiqhUyijVQrJFgjQS_gWIkUGINFNEBxZ9AEZBiOkCOQ-d-vImxyCYm33pvCDq9WOvL0dis_rf6z82_FPgCNsiQ3w</recordid><startdate>19891001</startdate><enddate>19891001</enddate><creator>Rud, Nathan P.</creator><creator>Reiman, Herbert M.</creator><creator>Pritchard, Douglas J.</creator><creator>Frassica, Frank J.</creator><creator>Smithson, William A.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19891001</creationdate><title>Extraosseous Ewing's sarcoma. A study of 42 cases</title><author>Rud, Nathan P. ; Reiman, Herbert M. ; Pritchard, Douglas J. ; Frassica, Frank J. ; Smithson, William A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5353-be27c3ca92c8a3cdad3142b47d2cb40281137bb369ee7424b1f7e9c5b70613a13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Back</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Combined Modality Therapy</topic><topic>Female</topic><topic>Foot</topic><topic>Humans</topic><topic>Infant</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Minnesota</topic><topic>Pelvis</topic><topic>Retrospective Studies</topic><topic>Sarcoma, Ewing - mortality</topic><topic>Sarcoma, Ewing - pathology</topic><topic>Sarcoma, Ewing - therapy</topic><topic>Soft Tissue Neoplasms - mortality</topic><topic>Soft Tissue Neoplasms - pathology</topic><topic>Soft Tissue Neoplasms - therapy</topic><topic>Thigh</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rud, Nathan P.</creatorcontrib><creatorcontrib>Reiman, Herbert M.</creatorcontrib><creatorcontrib>Pritchard, Douglas J.</creatorcontrib><creatorcontrib>Frassica, Frank J.</creatorcontrib><creatorcontrib>Smithson, William A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cancer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rud, Nathan P.</au><au>Reiman, Herbert M.</au><au>Pritchard, Douglas J.</au><au>Frassica, Frank J.</au><au>Smithson, William A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Extraosseous Ewing's sarcoma. A study of 42 cases</atitle><jtitle>Cancer</jtitle><addtitle>Cancer</addtitle><date>1989-10-01</date><risdate>1989</risdate><volume>64</volume><issue>7</issue><spage>1548</spage><epage>1553</epage><pages>1548-1553</pages><issn>0008-543X</issn><eissn>1097-0142</eissn><abstract>Fifty patients at the Mayo Clinic (Rochester, MN) from 1935 to 1985 met the histologic criteria for extraosseous Ewing's sarcoma. Forty‐two had soft tissue primaries without bony involvement and formed the basis for this retrospective study of the clinical behavior and management of extraosseous Ewing's sarcoma. There were 19 male and 23 female patients (mean age, 22 years). Metastases were documented in 30 of the patients, six at the time of presentation and 24 occurring up to 11 years later, most commonly to lungs or bone. Three patients were lost to follow‐up. Sixteen of 35 patients (46%) had local recurrence. Overall survival was 15 of 39 (38.5%) at 5 years. Decreased survival was noted with pelvic tumors, incomplete resections, and presence of metastatic disease, whereas increased survival was associated with wide surgical resection with negative microscopic margins, adjuvant local radiation therapy, and presentation since 1970 (48% 5‐year survival compared with 28% before 1970).</abstract><cop>New York</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>2776115</pmid><doi>10.1002/1097-0142(19891001)64:7<1548::AID-CNCR2820640733>3.0.CO;2-W</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0008-543X |
| ispartof | Cancer, 1989-10, Vol.64 (7), p.1548-1553 |
| issn | 0008-543X 1097-0142 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_79206953 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Adolescent Adult Aged Back Child Child, Preschool Combined Modality Therapy Female Foot Humans Infant Male Middle Aged Minnesota Pelvis Retrospective Studies Sarcoma, Ewing - mortality Sarcoma, Ewing - pathology Sarcoma, Ewing - therapy Soft Tissue Neoplasms - mortality Soft Tissue Neoplasms - pathology Soft Tissue Neoplasms - therapy Thigh |
| title | Extraosseous Ewing's sarcoma. A study of 42 cases |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-17T20%3A32%3A34IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Extraosseous%20Ewing's%20sarcoma.%20A%20study%20of%2042%20cases&rft.jtitle=Cancer&rft.au=Rud,%20Nathan%20P.&rft.date=1989-10-01&rft.volume=64&rft.issue=7&rft.spage=1548&rft.epage=1553&rft.pages=1548-1553&rft.issn=0008-543X&rft.eissn=1097-0142&rft_id=info:doi/10.1002/1097-0142(19891001)64:7%3C1548::AID-CNCR2820640733%3E3.0.CO;2-W&rft_dat=%3Cproquest_cross%3E79206953%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=79206953&rft_id=info:pmid/2776115&rfr_iscdi=true |