Effects of scopolamine on extracellular acetylcholine and choline levels and on spontaneous motor activity in freely moving rats measured by brain dialysis

The present study demonstrates the feasibility of measuring acetylcholine (ACh) and choline in perfusate samples collected by in vivo brain dialysis in the frontal cortex and hippocampus of freely moving rats in which spontaneous motor activity could be measured simultaneously. Systemically administ...

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Veröffentlicht in:	Pharmacology, biochemistry and behavior biochemistry and behavior, 1989-05, Vol.33 (1), p.109-113
1. Verfasser:	Toide, Katsuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine - metabolism Acetylcholine release Animals Biological and medical sciences Brain Chemistry - drug effects Brain dialysis Cerebral Cortex - drug effects Cerebral Cortex - metabolism Choline - metabolism Choline uptake Cholinergic system Chromatography, High Pressure Liquid Dialysis Electrochemistry Frontal cortex Hippocampus Hippocampus - drug effects Hippocampus - metabolism Male Medical sciences Motor Activity - drug effects Neuropharmacology Neurotransmitters. Neurotransmission. Receptors Pharmacology. Drug treatments Rats Rats, Inbred Strains Scopolamine Scopolamine - pharmacology Spontaneous motor activity Synaptic Transmission - drug effects
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