Characterization of a cDNA for rat P-450g, a highly polymorphic, male-specific cytochrome in the P-450IIC subfamily

Cytochrome P-450g (IIC13) is a highly polymorphic, male-specific rat liver isozyme which is a member of the P-450IIC subfamily. A cDNA, c5126 (1737 bp), for P-450g was isolated from a lambda gt11 library synthesized from (+g) male rat liver mRNA. Sequence analysis of the clone, c5126, revealed an op...

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Veröffentlicht in:	Biochemistry (Easton) 1989-07, Vol.28 (14), p.5832-5839
Hauptverfasser:	McClellan-Green, Patricia D, Negishi, Masahiko, Goldstein, Joyce A
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Analytical, structural and metabolic biochemistry Animals Base Sequence Biological and medical sciences Cytochrome P-450 Enzyme System - genetics DNA - genetics Female Fundamental and applied biological sciences. Psychology genes Hemoproteins Isoenzymes - genetics liver Male Metalloproteins Microsomes, Liver - enzymology Molecular Sequence Data Polymorphism, Genetic Proteins Rats Rats, Inbred Strains Sex Characteristics
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